Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial Carcinoma
Background: To evaluate the preoperative diagnostic efficacy of 3D-MRI for the depth of myometrial invasion of endometrial carcinoma. Methods: A total of 116 patients with endometrial carcinoma who had undergone pelvic MRI before surgery were included. Mimics 21.0 (Materialize Co., Belgium) software...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2022-09-01
|
| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/49/10/10.31083/j.ceog4910222 |
| _version_ | 1811337529285148672 |
|---|---|
| author | Jiaxin Fu Yuhui Cui Liqun Xu Ping Shen Xilong Liu Chunlin Chen Ping Liu |
| author_facet | Jiaxin Fu Yuhui Cui Liqun Xu Ping Shen Xilong Liu Chunlin Chen Ping Liu |
| author_sort | Jiaxin Fu |
| collection | DOAJ |
| description | Background: To evaluate the preoperative diagnostic efficacy of 3D-MRI for the depth of myometrial invasion of endometrial carcinoma. Methods: A total of 116 patients with endometrial carcinoma who had undergone pelvic MRI before surgery were included. Mimics 21.0 (Materialize Co., Belgium) software was used to reconstruct three-dimensional MRI models (3D-MRI). The tumor volume and surface area, uterine volume and surface area were measured, and the tumor volume ratio was calculated. TVR (Tumor Volume Ratio) = tumor volume/uterine volume, TAR (Tumor Area Ratio) = tumor surface area/uterine surface area. Postoperative pathology was used as the gold standard to compare the accuracy, sensitivity, specificity, negative predictive value, and positive predictive value of conventional MRI and 3D-MRI in preoperative assessment of endometrial carcinoma myometrial invasion. Results: The accuracy and specificity of 3D-MRI in the diagnosis of deep myometrial invasion were better than conventional MRI (p < 0.05). There was no statistically significant difference in tumor volume or surface area between stage IA and stage IB (p > 0.05), while TVR and TAR showed significant statistical differences (8.05 ± 0.66 vs. 19.12 ± 3.20, p < 0.01; 21.38 ± 1.04 vs. 35.15 ± 3.42, p < 0.01). Further analysis, the area under the ROC curve of TVR is 0.738, p < 0.01, and the best cut-off value is 13.59%; the area under the ROC curve of TAR is 0.770, p < 0.01, and the best cut-off value is 27.41%. Conclusions: Preoperative 3D-MRI can effectively assess the myometrial invasion of endometrial carcinoma. |
| first_indexed | 2024-04-13T17:56:23Z |
| format | Article |
| id | doaj.art-985392a2cc064833a38569e0b903e8e0 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-04-13T17:56:23Z |
| publishDate | 2022-09-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-985392a2cc064833a38569e0b903e8e02022-12-22T02:36:29ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632022-09-01491022210.31083/j.ceog4910222S0390-6663(22)01817-6Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial CarcinomaJiaxin Fu0Yuhui Cui1Liqun Xu2Ping Shen3Xilong Liu4Chunlin Chen5Ping Liu6Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, Guangdong, ChinaDepartment of Radiology, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, Guangdong, ChinaDepartment of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, Guangdong, ChinaDepartment of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, Guangdong, ChinaDepartment of Radiology, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, Guangdong, ChinaDepartment of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, Guangdong, ChinaDepartment of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, 510515 Guangzhou, Guangdong, ChinaBackground: To evaluate the preoperative diagnostic efficacy of 3D-MRI for the depth of myometrial invasion of endometrial carcinoma. Methods: A total of 116 patients with endometrial carcinoma who had undergone pelvic MRI before surgery were included. Mimics 21.0 (Materialize Co., Belgium) software was used to reconstruct three-dimensional MRI models (3D-MRI). The tumor volume and surface area, uterine volume and surface area were measured, and the tumor volume ratio was calculated. TVR (Tumor Volume Ratio) = tumor volume/uterine volume, TAR (Tumor Area Ratio) = tumor surface area/uterine surface area. Postoperative pathology was used as the gold standard to compare the accuracy, sensitivity, specificity, negative predictive value, and positive predictive value of conventional MRI and 3D-MRI in preoperative assessment of endometrial carcinoma myometrial invasion. Results: The accuracy and specificity of 3D-MRI in the diagnosis of deep myometrial invasion were better than conventional MRI (p < 0.05). There was no statistically significant difference in tumor volume or surface area between stage IA and stage IB (p > 0.05), while TVR and TAR showed significant statistical differences (8.05 ± 0.66 vs. 19.12 ± 3.20, p < 0.01; 21.38 ± 1.04 vs. 35.15 ± 3.42, p < 0.01). Further analysis, the area under the ROC curve of TVR is 0.738, p < 0.01, and the best cut-off value is 13.59%; the area under the ROC curve of TAR is 0.770, p < 0.01, and the best cut-off value is 27.41%. Conclusions: Preoperative 3D-MRI can effectively assess the myometrial invasion of endometrial carcinoma.https://www.imrpress.com/journal/CEOG/49/10/10.31083/j.ceog4910222endometrial carcinoma3d-mripreoperativetumor volumetumor surface |
| spellingShingle | Jiaxin Fu Yuhui Cui Liqun Xu Ping Shen Xilong Liu Chunlin Chen Ping Liu Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial Carcinoma Clinical and Experimental Obstetrics & Gynecology endometrial carcinoma 3d-mri preoperative tumor volume tumor surface |
| title | Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial Carcinoma |
| title_full | Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial Carcinoma |
| title_fullStr | Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial Carcinoma |
| title_full_unstemmed | Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial Carcinoma |
| title_short | Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial Carcinoma |
| title_sort | preoperative evaluation of 3d mri on the depth of myometrial invasion of endometrial carcinoma 3d study of endometrial carcinoma |
| topic | endometrial carcinoma 3d-mri preoperative tumor volume tumor surface |
| url | https://www.imrpress.com/journal/CEOG/49/10/10.31083/j.ceog4910222 |
| work_keys_str_mv | AT jiaxinfu preoperativeevaluationof3dmrionthedepthofmyometrialinvasionofendometrialcarcinoma3dstudyofendometrialcarcinoma AT yuhuicui preoperativeevaluationof3dmrionthedepthofmyometrialinvasionofendometrialcarcinoma3dstudyofendometrialcarcinoma AT liqunxu preoperativeevaluationof3dmrionthedepthofmyometrialinvasionofendometrialcarcinoma3dstudyofendometrialcarcinoma AT pingshen preoperativeevaluationof3dmrionthedepthofmyometrialinvasionofendometrialcarcinoma3dstudyofendometrialcarcinoma AT xilongliu preoperativeevaluationof3dmrionthedepthofmyometrialinvasionofendometrialcarcinoma3dstudyofendometrialcarcinoma AT chunlinchen preoperativeevaluationof3dmrionthedepthofmyometrialinvasionofendometrialcarcinoma3dstudyofendometrialcarcinoma AT pingliu preoperativeevaluationof3dmrionthedepthofmyometrialinvasionofendometrialcarcinoma3dstudyofendometrialcarcinoma |