Generation of induced pluripotent stem cell line, ICGi033-A, by reprogramming peripheral blood mononuclear cells from a patient with Huntington's disease

Generation of induced pluripotent stem cell line, ICGi033-A, by reprogramming peripheral blood mononuclear cells from a patient with Huntington's disease

Huntington's disease (HD) is a hereditary autosomal dominant neurodegenerative disease caused by the polyglutamine stretch expansion in the huntingtin (HTT) protein. In HD, dysregulation of multiple cellular processes occurs, resulting in the death of medium spiny neurons of striatum. A line of...

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Main Authors: Elena V. Grigor'eva, Anastasia A. Malakhova, Diana A. Sorogina, Sofia V. Pavlova, Tuyana B. Malankhanova, Natalia Yu. Abramycheva, Sergey A. Klyushnikov, Sergey N. Illarioshkin, Suren M. Zakian
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122002173

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