Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral Hemorrhage
ObjectiveThe purpose of this study is to investigate predictors of crossed cerebellar diaschisis (CCD), and the effects of CCD on functional outcomes including motor function, activities of daily living, cognitive function, and ambulation 6 months after onset in patients with intracerebral hemorrhag...
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| Format: | Article |
| Language: | English |
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Korean Academy of Rehabilitation Medicine
2018-02-01
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| Series: | Annals of Rehabilitation Medicine |
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| Online Access: | http://www.e-arm.org/upload/pdf/arm-42-8.pdf |
| _version_ | 1827837410629648384 |
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| author | Deok Su Sin Myoung Hyoun Kim Soon-Ah Park Min Cheol Joo Min Su Kim |
| author_facet | Deok Su Sin Myoung Hyoun Kim Soon-Ah Park Min Cheol Joo Min Su Kim |
| author_sort | Deok Su Sin |
| collection | DOAJ |
| description | ObjectiveThe purpose of this study is to investigate predictors of crossed cerebellar diaschisis (CCD), and the effects of CCD on functional outcomes including motor function, activities of daily living, cognitive function, and ambulation 6 months after onset in patients with intracerebral hemorrhage (ICH).MethodsA total of 74 patients experiencing their first ICH were recruited. If the asymmetric index was more than 10% using single photon emission computed tomography (SPECT), a diagnosis of CCD was confirmed. Clinical factors were retrospectively assessed by reviewing medical records. Radiologic factors encompassed the concomitance of intraventricular hemorrhage, side and location of the lesion, and hemorrhage volume. Functional outcomes were evaluated using the Fugl-Meyer Assessment, the Korean version of the Mini-Mental State Examination, the Korean version of the Modified Barthel Index, and measurement of the Functional Ambulatory Category at the time of SPECT measurement and 6 months post-ICH.ResultsLesion location, especially in the basal ganglia (odds ratio [OR]=6.138, p=0.011), and hemorrhagic volume (OR=1.055, p=0.046) were independent predictors for CCD according to multivariate logistic regression analysis. In addition, the presence of CCD was significantly related to the improvement in Fugl-Meyer Assessment score after 6 months (adjusted R2=0.152, p=0.036).ConclusionLesion location and hemorrhagic volume were the predisposing factors for CCD, and the CCD was associated with poor motor recovery over 6 months in patients with hemorrhagic stroke. |
| first_indexed | 2024-03-12T06:43:26Z |
| format | Article |
| id | doaj.art-985a094053bf497f91a1b9669b3a74c6 |
| institution | Directory Open Access Journal |
| issn | 2234-0645 2234-0653 |
| language | English |
| last_indexed | 2024-03-12T06:43:26Z |
| publishDate | 2018-02-01 |
| publisher | Korean Academy of Rehabilitation Medicine |
| record_format | Article |
| series | Annals of Rehabilitation Medicine |
| spelling | doaj.art-985a094053bf497f91a1b9669b3a74c62023-09-03T00:52:03ZengKorean Academy of Rehabilitation MedicineAnnals of Rehabilitation Medicine2234-06452234-06532018-02-0142181710.5535/arm.2018.42.1.8972Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral HemorrhageDeok Su Sin0Myoung Hyoun Kim1Soon-Ah Park2Min Cheol Joo3Min Su Kim4Department of Rehabilitation Medicine, Wonkwang University School of Medicine & Hospital, Iksan, Korea.Department of Nuclear Medicine, Wonkwang University School of Medicine & Hospital, Iksan, Korea.Department of Nuclear Medicine, Wonkwang University School of Medicine & Hospital, Iksan, Korea.Department of Rehabilitation Medicine, Wonkwang University School of Medicine & Hospital, Iksan, Korea.Department of Rehabilitation Medicine, Wonkwang University School of Medicine & Hospital, Iksan, Korea.ObjectiveThe purpose of this study is to investigate predictors of crossed cerebellar diaschisis (CCD), and the effects of CCD on functional outcomes including motor function, activities of daily living, cognitive function, and ambulation 6 months after onset in patients with intracerebral hemorrhage (ICH).MethodsA total of 74 patients experiencing their first ICH were recruited. If the asymmetric index was more than 10% using single photon emission computed tomography (SPECT), a diagnosis of CCD was confirmed. Clinical factors were retrospectively assessed by reviewing medical records. Radiologic factors encompassed the concomitance of intraventricular hemorrhage, side and location of the lesion, and hemorrhage volume. Functional outcomes were evaluated using the Fugl-Meyer Assessment, the Korean version of the Mini-Mental State Examination, the Korean version of the Modified Barthel Index, and measurement of the Functional Ambulatory Category at the time of SPECT measurement and 6 months post-ICH.ResultsLesion location, especially in the basal ganglia (odds ratio [OR]=6.138, p=0.011), and hemorrhagic volume (OR=1.055, p=0.046) were independent predictors for CCD according to multivariate logistic regression analysis. In addition, the presence of CCD was significantly related to the improvement in Fugl-Meyer Assessment score after 6 months (adjusted R2=0.152, p=0.036).ConclusionLesion location and hemorrhagic volume were the predisposing factors for CCD, and the CCD was associated with poor motor recovery over 6 months in patients with hemorrhagic stroke.http://www.e-arm.org/upload/pdf/arm-42-8.pdfCerebellumCerebral hemorrhageRecovery of functionRisk factorsSingle-photon emission-computed tomography |
| spellingShingle | Deok Su Sin Myoung Hyoun Kim Soon-Ah Park Min Cheol Joo Min Su Kim Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral Hemorrhage Annals of Rehabilitation Medicine Cerebellum Cerebral hemorrhage Recovery of function Risk factors Single-photon emission-computed tomography |
| title | Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral Hemorrhage |
| title_full | Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral Hemorrhage |
| title_fullStr | Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral Hemorrhage |
| title_full_unstemmed | Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral Hemorrhage |
| title_short | Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral Hemorrhage |
| title_sort | crossed cerebellar diaschisis risk factors and correlation to functional recovery in intracerebral hemorrhage |
| topic | Cerebellum Cerebral hemorrhage Recovery of function Risk factors Single-photon emission-computed tomography |
| url | http://www.e-arm.org/upload/pdf/arm-42-8.pdf |
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