Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1α/PPAR-α Players

Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1α/PPAR-α Players

Stem cells are a population of undifferentiated cells with self-renewal and differentiation capacities. Normal and cancer stem cells share similar characteristics in relation to their stemness properties. One-carbon metabolism (OCM), a network of interconnected reactions, plays an important role in...

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Bibliographic Details
Main Authors: Youssef Siblini, Farès Namour, Abderrahim Oussalah, Jean-Louis Guéant, Céline Chéry
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
normal stem cells
cancer stem cells
methionine
methionine dependence
stemness
sirtuin 1
Online Access:https://www.mdpi.com/2073-4409/11/22/3607

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