Translocation Renal Cell Carcinoma: An Update on Clinicopathological and Molecular Features

Translocation Renal Cell Carcinoma: An Update on Clinicopathological and Molecular Features

Microphthalmia-associated transcription (MiT) family translocation renal cell carcinoma (tRCC) comprises Xp11 tRCC and t(6;11) RCC. Due to the presence of fusion genes, Xp11 tRCC and t(6;11) RCC are also known as TFE3- and TFEB-rearranged RCC, respectively. TFE3 and TFEB belong to the MiT family, wh...

Full description

Bibliographic Details
Main Author:	Kentaro Inamura
Format:	Article
Language:	English
Published:	MDPI AG 2017-08-01
Series:	Cancers
Subjects:	ALK fusion kidney renal cell carcinoma TFE3 TFEB translocation
Online Access:	https://www.mdpi.com/2072-6694/9/9/111

Similar Items

MiTF/TFE Translocation Renal Cell Carcinomas: From Clinical Entities to Molecular Insights
by: Audrey Simonaggio, et al.
Published: (2022-07-01)

MiT Family Translocation Renal Cell Carcinoma: from the Early Descriptions to the Current Knowledge
by: Anna Caliò, et al.
Published: (2019-08-01)

Exploration of clinicopathological features of rearranged renal cell carcinoma and TFE3, TFEB, and ALK staining performance in renal entities
by: Yang Liu, et al.
Published: (2023-04-01)

Clinicopathologic, treatment and prognosis study of 46 Xp11.2 translocation/TFE3 gene fusion renal cell carcinomas
by: Jiale Zhou, et al.
Published: (2022-07-01)

Xp11 Translocation Renal Cell Carcinoma: Unusual Variant Masquerading as Upper Tract Urothelial Cell Carcinoma
by: Arash Akhavein, et al.
Published: (2014-05-01)

MiT/TFE Family Renal Cell Carcinoma
by: Jinglong Tang, et al.
Published: (2023-01-01)

SEARCH FOR ARE REGULATORY SEQUENCES IN GENES of MASTER REGULATORS OF autophagy and LYSOSOMAL BIOGENESIS TFEB AND TFE3
by: A. V. Chechushkov, et al.
Published: (2019-02-01)

Xp11.2 Translocation Renal Cell Carcinoma With TFE3 Rearrangement: Distinct Morphological Features and Prognosis With Different Fusion Partners
by: Yan Ge, et al.
Published: (2021-11-01)

The preliminary experiences of translocation renal cell carcinoma and literature review
by: Hsin-Hao Su, et al.
Published: (2014-08-01)

Bilateral Xp11.2 translocation renal cell carcinoma: a case report
by: Takashi Karashima, et al.
Published: (2018-11-01)

Clinicopathological features and prognosis of TFE3-positive renal cell carcinoma
by: Xiang Dong, et al.
Published: (2022-10-01)

Morphological spectrum of Xp11. Translocation-Associated Renal Cell Carcinoma in a Developing Country
by: Iram Khan, et al.
Published: (2022-11-01)

The incidence of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion in Saudi adult patients with renal cancer: a retrospective tissue microarray analysis
by: Jaudah Al-Maghrabi, et al.
Published: (2019-01-01)

Molecular Heterogeneity of Xp11.2 Translocation Renal Cell Carcinoma: The Correlation Between Split Signal Pattern in FISH and Prognosis
by: Zhu Y, et al.
Published: (2021-03-01)

Sarcomatoid variant of Xp11 translocation renal cell carcinoma: A rare case report in an adult female
by: Rakhi V Jagdale, et al.
Published: (2024-01-01)

TFEB and TFE3 drive kidney cystogenesis and tumorigenesis
by: Chiara Di Malta, et al.
Published: (2023-05-01)

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma
by: Martin Lang, et al.
Published: (2023-04-01)

Melanotic Xp11 translocation renal cancer: a report of a distinctive case and a review of the literature
by: Hongbiao Jing, et al.
Published: (2018-08-01)

MiT family translocation renal cell carcinoma with retroperitoneal metastasis in childhood: a case report
by: Kaihang Yang, et al.
Published: (2023-07-01)

Clinical and pathological heterogeneity of four common fusion subtypes in Xp11.2 translocation renal cell carcinoma
by: Wei Guo, et al.
Published: (2023-02-01)

A safe and effective treatment combination of neoadjuvant therapy and surgical resection for metastatic TFE3-rearranged renal cell carcinoma:a case report
by: Haiyang Yang, et al.
Published: (2023-10-01)

Emerging roles and regulation of MiT/TFE transcriptional factors
by: Min Yang, et al.
Published: (2018-06-01)

Immune checkpoint inhibitors in MITF family translocation renal cell carcinomas and genetic correlates of exceptional responders
by: A. Boilève, et al.
Published: (2018-12-01)

Are tumor-associated micro-angiogenesis and lymphangiogenesis considered as the novel prognostic factors for patients with Xp11.2 translocation renal cell carcinoma?
by: Wenliang Ma, et al.
Published: (2020-12-01)

Case Report: TFE3 Positive Xp11.2 Translocation Renal Cell Carcinoma (TRCC) – A Case Study and Review of the Literature
by: Ignacy Miroński, et al.
Published: (2022-01-01)

Both SUMOylation and ubiquitination of TFE3 fusion protein regulated by androgen receptor are the potential target in the therapy of Xp11.2 translocation renal cell carcinoma
by: Ning Liu, et al.
Published: (2022-04-01)

Proteasome Inhibition Activates Autophagy-Lysosome Pathway Associated With TFEB Dephosphorylation and Nuclear Translocation
by: Chunyan Li, et al.
Published: (2019-08-01)

TFE3 gene rearrangement and protein expression contribute to a poor prognosis of renal cell carcinoma
by: Junyi Lin, et al.
Published: (2023-05-01)

6p21 translocation renal cell carcinoma: A case report
by: Yuho Sano, et al.
Published: (2021-01-01)

Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells
by: Kentaro Oh-hashi, et al.
Published: (2023-03-01)

TFE3-rearranged renal cell carcinoma with tumour thrombus in the ureter mimicking invasive transitional cell carcinoma
by: Arman Z. Chacko, et al.
Published: (2023-11-01)

Xp11.2 translocation renal carcinoma in a child
by: Gloria Paredes-Guerra, et al.
Published: (2020-01-01)

MiT Family Translocation Renal Cell Carcinomas
by: Ayça Tan, et al.
Published: (2016-09-01)

Kidney carcinoma associated with Xp11.2 translocation / TFE3 (ASPL-TFE3) gene fusion
by: Paulo G. O. Salles, et al.
Published: (2005-06-01)

Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
by: Alessia Calcagnì, et al.
Published: (2016-09-01)

Xp11.2 Translocation Renal Cell Carcinoma Diagnosed by Immunohistochemistry and Cytogenetics
by: Biswajit Dey, et al.
Published: (2016-07-01)

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB
by: Guo Chen, et al.
Published: (2019-11-01)

Valosin Containing Protein (VCP): A Multistep Regulator of Autophagy
by: Veronica Ferrari, et al.
Published: (2022-02-01)

Review of TFEB-amplified renal cell carcinoma with focus on clinical and pathobiological aspects
by: Naoto Kuroda, et al.
Published: (2022-01-01)

Gene Expression Analysis of Aggressive Adult Xp11.2 Translocation Renal Cell Carcinoma at Clinical Stage T1N0M0 to Identify Potential Prognostic and Therapeutic Biomarkers
by: Jee Soo Park, et al.
Published: (2022-01-01)