Neuroinformatics: From Bioinformatics to Databasing the Brain

Neuroinformatics seeks to create and maintain web-accessible databases of experimental and computational data, together with innovative software tools, essential for understanding the nervous system in its normal function and in neurological disorders. Neuroinformatics includes traditional bioinform...

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Main Author: Thomas M . Morse
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Bioinformatics and Biology Insights
Subjects:
Online Access:http://la-press.com/article.php?article_id=778
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author Thomas M . Morse
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author_sort Thomas M . Morse
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description Neuroinformatics seeks to create and maintain web-accessible databases of experimental and computational data, together with innovative software tools, essential for understanding the nervous system in its normal function and in neurological disorders. Neuroinformatics includes traditional bioinformatics of gene and protein sequences in the brain; atlases of brain anatomy and localization of genes and proteins; imaging of brain cells; brain imaging by positron emission tomography (PET), functional magnetic resonance imaging (fMRI), electroencephalography (EEG), magnetoencephalography (MEG) and other methods; many electrophysiological recording methods; and clinical neurological data, among others. Building neuroinformatics databases and tools presents difficult challenges because they span a wide range of spatial scales and types of data stored and analyzed. Traditional bioinformatics, by comparison, focuses primarily on genomic and proteomic data (which of course also presents difficult challenges). Much of bioinformatics analysis focus on sequences (DNA, RNA, and protein molecules), as the type of data that are stored, compared, and sometimes modeled. Bioinformatics is undergoing explosive growth with the addition, for example, of databases that catalog interactions between proteins, of databases that track the evolution of genes, and of systems biology databases which contain models of all aspects of organisms. This commentary briefly reviews neuroinformatics with clarification of its relationship to traditional and modern bioinformatics.
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spelling doaj.art-98695e585a394d2ab74b4f987713c0e12022-12-21T18:58:53ZengSAGE PublishingBioinformatics and Biology Insights1177-93222008-01-012259270Neuroinformatics: From Bioinformatics to Databasing the BrainThomas M . MorseNeuroinformatics seeks to create and maintain web-accessible databases of experimental and computational data, together with innovative software tools, essential for understanding the nervous system in its normal function and in neurological disorders. Neuroinformatics includes traditional bioinformatics of gene and protein sequences in the brain; atlases of brain anatomy and localization of genes and proteins; imaging of brain cells; brain imaging by positron emission tomography (PET), functional magnetic resonance imaging (fMRI), electroencephalography (EEG), magnetoencephalography (MEG) and other methods; many electrophysiological recording methods; and clinical neurological data, among others. Building neuroinformatics databases and tools presents difficult challenges because they span a wide range of spatial scales and types of data stored and analyzed. Traditional bioinformatics, by comparison, focuses primarily on genomic and proteomic data (which of course also presents difficult challenges). Much of bioinformatics analysis focus on sequences (DNA, RNA, and protein molecules), as the type of data that are stored, compared, and sometimes modeled. Bioinformatics is undergoing explosive growth with the addition, for example, of databases that catalog interactions between proteins, of databases that track the evolution of genes, and of systems biology databases which contain models of all aspects of organisms. This commentary briefly reviews neuroinformatics with clarification of its relationship to traditional and modern bioinformatics.http://la-press.com/article.php?article_id=778comparisonsimilaritydifferenceoverlapunderstandbetween
spellingShingle Thomas M . Morse
Neuroinformatics: From Bioinformatics to Databasing the Brain
Bioinformatics and Biology Insights
comparison
similarity
difference
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understand
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title Neuroinformatics: From Bioinformatics to Databasing the Brain
title_full Neuroinformatics: From Bioinformatics to Databasing the Brain
title_fullStr Neuroinformatics: From Bioinformatics to Databasing the Brain
title_full_unstemmed Neuroinformatics: From Bioinformatics to Databasing the Brain
title_short Neuroinformatics: From Bioinformatics to Databasing the Brain
title_sort neuroinformatics from bioinformatics to databasing the brain
topic comparison
similarity
difference
overlap
understand
between
url http://la-press.com/article.php?article_id=778
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