Spontaneous EBV-Reactivation during B Cell Differentiation as a Model for Polymorphic EBV-Driven Lymphoproliferation

Spontaneous EBV-Reactivation during B Cell Differentiation as a Model for Polymorphic EBV-Driven Lymphoproliferation

Epstein-Barr virus (EBV)-driven B cell neoplasms arise from the reactivation of latently infected B cells. In a subset of patients, EBV was seen to drive a polymorphous lymphoproliferative disorder (LPD) in which B cell differentiation was retained. In this work, spontaneous EBV reactivation followi...

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Bibliographic Details
Main Authors: Matthew A. Care, Sophie Stephenson, Roger Owen, Gina M. Doody, Reuben M. Tooze
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
Epstein-Barr virus
B-cell
germinal centre
plasma cell
latency
reactivation
Online Access:https://www.mdpi.com/2072-6694/15/12/3083

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