Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation
Ruptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulat...
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MDPI AG
2023-10-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/13/11/1507 |
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| author | Minghui Zhou Zengbao Wu Ali Abdi Maalim Ying Zeng Xiao Guo Zhenhua Zhang Xiaohong Yuan Zacharia Majaliwa Enos Kai Shu Ting Lei Mingxin Zhu |
| author_facet | Minghui Zhou Zengbao Wu Ali Abdi Maalim Ying Zeng Xiao Guo Zhenhua Zhang Xiaohong Yuan Zacharia Majaliwa Enos Kai Shu Ting Lei Mingxin Zhu |
| author_sort | Minghui Zhou |
| collection | DOAJ |
| description | Ruptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulation dissecting aneurysms (PCDAs). Their average age was 52 years. We selected 11 patients who used Enterprise (EP) and LVIS stents overlappingly and matched them 1:1 with counterparts who received either EP or LVIS stents individually. Overlapping stents was a feasible treatment in all 27 cases. We successfully followed up 26 patients for ≥6 months. Regrettably, one patient died from intracranial hypertension on Day 7 post-procedure. Immediate post-procedure angiographies indicated Raymond grade I, II, and III occlusions of PCDAs in 16 (59.3%), 7 (25.9%), and 4 (14.8%) cases, respectively. At an average follow-up duration of 16.2 months, 25 patients (96.2%) had modified Rankin Scale scores of 0–2, signifying positive outcomes. One patient (3.8%) had a score of 3–4. Recurrence rates for the EP and LVIS stent groups were higher than those of the overlapping stent group (45.45% vs. 9.09%, <i>p</i> = 0.15 and 27.27% vs. 9.09%, <i>p</i> = 0.59, respectively). No significant difference in recurrence rates existed between the overlapping and single-stent groups. Similarly, follow-up outcomes were consistent between the two groups. Overlapping stents could be an efficient method for treating ruptured PCDAs. |
| first_indexed | 2024-03-09T16:58:48Z |
| format | Article |
| id | doaj.art-986d3c91d854495b83941554fc3c37a0 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-09T16:58:48Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-986d3c91d854495b83941554fc3c37a02023-11-24T14:32:31ZengMDPI AGBrain Sciences2076-34252023-10-011311150710.3390/brainsci13111507Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior CirculationMinghui Zhou0Zengbao Wu1Ali Abdi Maalim2Ying Zeng3Xiao Guo4Zhenhua Zhang5Xiaohong Yuan6Zacharia Majaliwa Enos7Kai Shu8Ting Lei9Mingxin Zhu10Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Tianyou Hospital Affiliated to Wuhan University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, ChinaRuptured dissecting aneurysms in posterior intracranial circulation present significant clinical challenges and often cause poor prognoses. Our cohort used overlapping stents as the primary treatment. We analyzed the medical records of 27 patients (18 men/nine women) with ruptured posterior circulation dissecting aneurysms (PCDAs). Their average age was 52 years. We selected 11 patients who used Enterprise (EP) and LVIS stents overlappingly and matched them 1:1 with counterparts who received either EP or LVIS stents individually. Overlapping stents was a feasible treatment in all 27 cases. We successfully followed up 26 patients for ≥6 months. Regrettably, one patient died from intracranial hypertension on Day 7 post-procedure. Immediate post-procedure angiographies indicated Raymond grade I, II, and III occlusions of PCDAs in 16 (59.3%), 7 (25.9%), and 4 (14.8%) cases, respectively. At an average follow-up duration of 16.2 months, 25 patients (96.2%) had modified Rankin Scale scores of 0–2, signifying positive outcomes. One patient (3.8%) had a score of 3–4. Recurrence rates for the EP and LVIS stent groups were higher than those of the overlapping stent group (45.45% vs. 9.09%, <i>p</i> = 0.15 and 27.27% vs. 9.09%, <i>p</i> = 0.59, respectively). No significant difference in recurrence rates existed between the overlapping and single-stent groups. Similarly, follow-up outcomes were consistent between the two groups. Overlapping stents could be an efficient method for treating ruptured PCDAs.https://www.mdpi.com/2076-3425/13/11/1507overlapping stentsruptured dissecting aneurysmsposterior circulationendovascular treatment |
| spellingShingle | Minghui Zhou Zengbao Wu Ali Abdi Maalim Ying Zeng Xiao Guo Zhenhua Zhang Xiaohong Yuan Zacharia Majaliwa Enos Kai Shu Ting Lei Mingxin Zhu Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation Brain Sciences overlapping stents ruptured dissecting aneurysms posterior circulation endovascular treatment |
| title | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
| title_full | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
| title_fullStr | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
| title_full_unstemmed | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
| title_short | Overlapping Stent Treatment for Ruptured Dissecting Aneurysms in Posterior Circulation |
| title_sort | overlapping stent treatment for ruptured dissecting aneurysms in posterior circulation |
| topic | overlapping stents ruptured dissecting aneurysms posterior circulation endovascular treatment |
| url | https://www.mdpi.com/2076-3425/13/11/1507 |
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