The Jena Method: Perfusionist Independent, Standby Wet-Primed Extracorporeal Membrane Oxygenation (ECMO) Circuit for Immediate Catheterization Laboratory and/or Hybrid Operating Room Deployment

<b>Background:</b> The timely initiation of extracorporeal membrane oxygenation (ECMO) is crucial for providing life support. However, delays can occur when perfusionists are not readily available. The Jena Method aims to address this issue by offering a wet-primed ECMO system that can b...

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Main Authors: Franz Haertel, Mirko Kaluza, Jurgen Bogoviku, Julian Westphal, Michael Fritzenwanger, Ruediger Pfeifer, Daniel Kretzschmar, Torsten Doenst, Sven Moebius-Winkler, P. Christian Schulze
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/13/5/1292
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author Franz Haertel
Mirko Kaluza
Jurgen Bogoviku
Julian Westphal
Michael Fritzenwanger
Ruediger Pfeifer
Daniel Kretzschmar
Torsten Doenst
Sven Moebius-Winkler
P. Christian Schulze
author_facet Franz Haertel
Mirko Kaluza
Jurgen Bogoviku
Julian Westphal
Michael Fritzenwanger
Ruediger Pfeifer
Daniel Kretzschmar
Torsten Doenst
Sven Moebius-Winkler
P. Christian Schulze
author_sort Franz Haertel
collection DOAJ
description <b>Background:</b> The timely initiation of extracorporeal membrane oxygenation (ECMO) is crucial for providing life support. However, delays can occur when perfusionists are not readily available. The Jena Method aims to address this issue by offering a wet-primed ECMO system that can be rapidly established without the perfusionist’s presence. <b>Methods:</b> The goal was to ensure prompt ECMO initiation while maintaining patient safety. The method focuses on meeting hygienic standards, safe primed storage of the circuit, staff training, and providing clear step-by-step instructions for the ECMO unit. <b>Results:</b> Since implementing the Jena Method in 2015, 306 patients received VA-ECMO treatment. Bacterial tests confirmed the sterility of the primed ECMO circuits during a 14-day period. The functionality of all the components of the primed ECMO circuit after 14 days, especially the pump and oxygenator, were thoroughly checked and no malfunction was found to this day. To train staff for independent ECMO initiation, a step-by-step system involves safely bringing the ECMO unit to the intervention site and establishing all connections. This includes powering up, managing recirculation, de-airing the system, and preparing it for cannula connection. A self-developed picture-based guide assists in this process. New staff members learn from colleagues and receive quarterly training sessions by perfusionists. After ECMO deployment, the perfusionist provides a new primed system for a potential next patient. <b>Conclusions:</b> Establishing a permanently wet-primed on-demand extracorporeal life support circuit without direct perfusionist support is feasible and safe. The Jena Method enables rapid ECMO deployment and has the potential to be adopted in emergency departments as well.
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spelling doaj.art-986e13bb280c4c539951f139e6d245562024-03-12T16:47:52ZengMDPI AGJournal of Clinical Medicine2077-03832024-02-01135129210.3390/jcm13051292The Jena Method: Perfusionist Independent, Standby Wet-Primed Extracorporeal Membrane Oxygenation (ECMO) Circuit for Immediate Catheterization Laboratory and/or Hybrid Operating Room DeploymentFranz Haertel0Mirko Kaluza1Jurgen Bogoviku2Julian Westphal3Michael Fritzenwanger4Ruediger Pfeifer5Daniel Kretzschmar6Torsten Doenst7Sven Moebius-Winkler8P. Christian Schulze9Department of Internal Medicine I, Cardiology, University Hospital Jena, Am Klinikum 1, 07747 Jena, GermanyDepartment of Cardiothoracic Surgery, University Hospital Jena, Am Klinikum 1, 07747 Jena, GermanyDepartment of Internal Medicine I, Cardiology, University Hospital Jena, Am Klinikum 1, 07747 Jena, GermanyDepartment of Internal Medicine I, Cardiology, University Hospital Jena, Am Klinikum 1, 07747 Jena, GermanyDepartment of Internal Medicine I, Cardiology, University Hospital Jena, Am Klinikum 1, 07747 Jena, GermanyDepartment of Internal Medicine I, Cardiology, University Hospital Jena, Am Klinikum 1, 07747 Jena, GermanyHeart and Vascular Medicine (HUGG), Fleischscharren 4, 38642 Goslar, GermanyDepartment of Cardiothoracic Surgery, University Hospital Jena, Am Klinikum 1, 07747 Jena, GermanyDepartment of Internal Medicine I, Cardiology, University Hospital Jena, Am Klinikum 1, 07747 Jena, GermanyDepartment of Internal Medicine I, Cardiology, University Hospital Jena, Am Klinikum 1, 07747 Jena, Germany<b>Background:</b> The timely initiation of extracorporeal membrane oxygenation (ECMO) is crucial for providing life support. However, delays can occur when perfusionists are not readily available. The Jena Method aims to address this issue by offering a wet-primed ECMO system that can be rapidly established without the perfusionist’s presence. <b>Methods:</b> The goal was to ensure prompt ECMO initiation while maintaining patient safety. The method focuses on meeting hygienic standards, safe primed storage of the circuit, staff training, and providing clear step-by-step instructions for the ECMO unit. <b>Results:</b> Since implementing the Jena Method in 2015, 306 patients received VA-ECMO treatment. Bacterial tests confirmed the sterility of the primed ECMO circuits during a 14-day period. The functionality of all the components of the primed ECMO circuit after 14 days, especially the pump and oxygenator, were thoroughly checked and no malfunction was found to this day. To train staff for independent ECMO initiation, a step-by-step system involves safely bringing the ECMO unit to the intervention site and establishing all connections. This includes powering up, managing recirculation, de-airing the system, and preparing it for cannula connection. A self-developed picture-based guide assists in this process. New staff members learn from colleagues and receive quarterly training sessions by perfusionists. After ECMO deployment, the perfusionist provides a new primed system for a potential next patient. <b>Conclusions:</b> Establishing a permanently wet-primed on-demand extracorporeal life support circuit without direct perfusionist support is feasible and safe. The Jena Method enables rapid ECMO deployment and has the potential to be adopted in emergency departments as well.https://www.mdpi.com/2077-0383/13/5/1292ECMOECLSprimed circuitwet circuitcardiac resuscitationlow cardiac output support
spellingShingle Franz Haertel
Mirko Kaluza
Jurgen Bogoviku
Julian Westphal
Michael Fritzenwanger
Ruediger Pfeifer
Daniel Kretzschmar
Torsten Doenst
Sven Moebius-Winkler
P. Christian Schulze
The Jena Method: Perfusionist Independent, Standby Wet-Primed Extracorporeal Membrane Oxygenation (ECMO) Circuit for Immediate Catheterization Laboratory and/or Hybrid Operating Room Deployment
Journal of Clinical Medicine
ECMO
ECLS
primed circuit
wet circuit
cardiac resuscitation
low cardiac output support
title The Jena Method: Perfusionist Independent, Standby Wet-Primed Extracorporeal Membrane Oxygenation (ECMO) Circuit for Immediate Catheterization Laboratory and/or Hybrid Operating Room Deployment
title_full The Jena Method: Perfusionist Independent, Standby Wet-Primed Extracorporeal Membrane Oxygenation (ECMO) Circuit for Immediate Catheterization Laboratory and/or Hybrid Operating Room Deployment
title_fullStr The Jena Method: Perfusionist Independent, Standby Wet-Primed Extracorporeal Membrane Oxygenation (ECMO) Circuit for Immediate Catheterization Laboratory and/or Hybrid Operating Room Deployment
title_full_unstemmed The Jena Method: Perfusionist Independent, Standby Wet-Primed Extracorporeal Membrane Oxygenation (ECMO) Circuit for Immediate Catheterization Laboratory and/or Hybrid Operating Room Deployment
title_short The Jena Method: Perfusionist Independent, Standby Wet-Primed Extracorporeal Membrane Oxygenation (ECMO) Circuit for Immediate Catheterization Laboratory and/or Hybrid Operating Room Deployment
title_sort jena method perfusionist independent standby wet primed extracorporeal membrane oxygenation ecmo circuit for immediate catheterization laboratory and or hybrid operating room deployment
topic ECMO
ECLS
primed circuit
wet circuit
cardiac resuscitation
low cardiac output support
url https://www.mdpi.com/2077-0383/13/5/1292
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