Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy
Analyzing biomolecules is essential for disease diagnostics, food safety inspection, environmental monitoring and pharmaceutical development. Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for detecting biomolecules due to its high sensitivity, rapidness and specificity in identifying...
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Format: | Article |
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MDPI AG
2018-09-01
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Series: | Nanomaterials |
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Online Access: | http://www.mdpi.com/2079-4991/8/9/730 |
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author | Min Jia Shenmiao Li Liguo Zang Xiaonan Lu Hongyan Zhang |
author_facet | Min Jia Shenmiao Li Liguo Zang Xiaonan Lu Hongyan Zhang |
author_sort | Min Jia |
collection | DOAJ |
description | Analyzing biomolecules is essential for disease diagnostics, food safety inspection, environmental monitoring and pharmaceutical development. Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for detecting biomolecules due to its high sensitivity, rapidness and specificity in identifying molecular structures. This review focuses on the SERS analysis of biomolecules originated from humans, animals, plants and microorganisms, combined with nanomaterials as SERS substrates and nanotags. Recent advances in SERS detection of target molecules were summarized with different detection strategies including label-free and label-mediated types. This comprehensive and critical summary of SERS analysis of biomolecules might help researchers from different scientific backgrounds spark new ideas and proposals. |
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format | Article |
id | doaj.art-986eeeab90d445f7b1dfc2c44bf1fd72 |
institution | Directory Open Access Journal |
issn | 2079-4991 |
language | English |
last_indexed | 2024-12-21T19:14:43Z |
publishDate | 2018-09-01 |
publisher | MDPI AG |
record_format | Article |
series | Nanomaterials |
spelling | doaj.art-986eeeab90d445f7b1dfc2c44bf1fd722022-12-21T18:53:06ZengMDPI AGNanomaterials2079-49912018-09-018973010.3390/nano8090730nano8090730Analysis of Biomolecules Based on the Surface Enhanced Raman SpectroscopyMin Jia0Shenmiao Li1Liguo Zang2Xiaonan Lu3Hongyan Zhang4Shandong Provincial Key Laboratory of Animal Resistance Biology, Institute of Biomedical Sciences, Key Laboratory of Food Nutrition and Safety of Shandong Normal University, College of Life Science, Shandong Normal University, Jinan 250014, ChinaFood, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T 1Z4, CanadaShandong Provincial Key Laboratory of Animal Resistance Biology, Institute of Biomedical Sciences, Key Laboratory of Food Nutrition and Safety of Shandong Normal University, College of Life Science, Shandong Normal University, Jinan 250014, ChinaFood, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T 1Z4, CanadaShandong Provincial Key Laboratory of Animal Resistance Biology, Institute of Biomedical Sciences, Key Laboratory of Food Nutrition and Safety of Shandong Normal University, College of Life Science, Shandong Normal University, Jinan 250014, ChinaAnalyzing biomolecules is essential for disease diagnostics, food safety inspection, environmental monitoring and pharmaceutical development. Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for detecting biomolecules due to its high sensitivity, rapidness and specificity in identifying molecular structures. This review focuses on the SERS analysis of biomolecules originated from humans, animals, plants and microorganisms, combined with nanomaterials as SERS substrates and nanotags. Recent advances in SERS detection of target molecules were summarized with different detection strategies including label-free and label-mediated types. This comprehensive and critical summary of SERS analysis of biomolecules might help researchers from different scientific backgrounds spark new ideas and proposals.http://www.mdpi.com/2079-4991/8/9/730biomoleculesurface enhanced Raman spectroscopy (SERS)nanomaterialanalysisidentificationbiology |
spellingShingle | Min Jia Shenmiao Li Liguo Zang Xiaonan Lu Hongyan Zhang Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy Nanomaterials biomolecule surface enhanced Raman spectroscopy (SERS) nanomaterial analysis identification biology |
title | Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy |
title_full | Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy |
title_fullStr | Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy |
title_full_unstemmed | Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy |
title_short | Analysis of Biomolecules Based on the Surface Enhanced Raman Spectroscopy |
title_sort | analysis of biomolecules based on the surface enhanced raman spectroscopy |
topic | biomolecule surface enhanced Raman spectroscopy (SERS) nanomaterial analysis identification biology |
url | http://www.mdpi.com/2079-4991/8/9/730 |
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