Measuring integrated HIV DNA ex vivo and in vitro provides insights about how reservoirs are formed and maintained

Abstract The identification of the most appropriate marker to measure reservoir size has been a great challenge for the HIV field. Quantitative viral outgrowth assay (QVOA), the reference standard to quantify the amount of replication-competent virus, has several limitations, as it is laborious, exp...

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Bibliographic Details
Main Authors: Marilia Rita Pinzone, Una O’Doherty
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Retrovirology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12977-018-0396-3