Progress in the treatment of neovascular age-related macular degeneration

Age-related macular degeneration(ARMD)is an important cause of visual impairment in people over 65 years old in western countries. It is the third leading cause of blindness in China and mainly affects central visual acuity. Vascular endothelial growth factor(VEGF)plays an important role in the path...

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Main Authors: Ya-Xin Wang, Xiao-Yun Ke, Yan-Xia Chen, Bin Hu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-10-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2021/10/202110014.pdf
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author Ya-Xin Wang
Xiao-Yun Ke
Yan-Xia Chen
Bin Hu
author_facet Ya-Xin Wang
Xiao-Yun Ke
Yan-Xia Chen
Bin Hu
author_sort Ya-Xin Wang
collection DOAJ
description Age-related macular degeneration(ARMD)is an important cause of visual impairment in people over 65 years old in western countries. It is the third leading cause of blindness in China and mainly affects central visual acuity. Vascular endothelial growth factor(VEGF)plays an important role in the pathogenesis of ARMD. Currently, intravitreous injection of anti-VEGF agents has been considered as the first-line treatment for ARMD. However, some patients still need repeated injection, or response negatively to anti-VEGF agents. Therefore, it is necessary to explore novel therapy to improve clinical outcomes and provide insights for neovascular ARMD treatment.
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spelling doaj.art-9872a7d4288445f796601fd439d83ce52022-12-21T21:32:59ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232021-10-0121101732173510.3980/j.issn.1672-5123.2021.10.14202110014Progress in the treatment of neovascular age-related macular degenerationYa-Xin Wang0Xiao-Yun Ke1Yan-Xia Chen2Bin Hu3Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, Guangdong Province, ChinaDepartment of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, Guangdong Province, ChinaDepartment of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, Guangdong Province, ChinaDepartment of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, Guangdong Province, ChinaAge-related macular degeneration(ARMD)is an important cause of visual impairment in people over 65 years old in western countries. It is the third leading cause of blindness in China and mainly affects central visual acuity. Vascular endothelial growth factor(VEGF)plays an important role in the pathogenesis of ARMD. Currently, intravitreous injection of anti-VEGF agents has been considered as the first-line treatment for ARMD. However, some patients still need repeated injection, or response negatively to anti-VEGF agents. Therefore, it is necessary to explore novel therapy to improve clinical outcomes and provide insights for neovascular ARMD treatment.http://ies.ijo.cn/cn_publish/2021/10/202110014.pdfneovascular age-related macular degenerationvascular endothelial growth factorplatelet derived growth factortherapeutic progress
spellingShingle Ya-Xin Wang
Xiao-Yun Ke
Yan-Xia Chen
Bin Hu
Progress in the treatment of neovascular age-related macular degeneration
Guoji Yanke Zazhi
neovascular age-related macular degeneration
vascular endothelial growth factor
platelet derived growth factor
therapeutic progress
title Progress in the treatment of neovascular age-related macular degeneration
title_full Progress in the treatment of neovascular age-related macular degeneration
title_fullStr Progress in the treatment of neovascular age-related macular degeneration
title_full_unstemmed Progress in the treatment of neovascular age-related macular degeneration
title_short Progress in the treatment of neovascular age-related macular degeneration
title_sort progress in the treatment of neovascular age related macular degeneration
topic neovascular age-related macular degeneration
vascular endothelial growth factor
platelet derived growth factor
therapeutic progress
url http://ies.ijo.cn/cn_publish/2021/10/202110014.pdf
work_keys_str_mv AT yaxinwang progressinthetreatmentofneovascularagerelatedmaculardegeneration
AT xiaoyunke progressinthetreatmentofneovascularagerelatedmaculardegeneration
AT yanxiachen progressinthetreatmentofneovascularagerelatedmaculardegeneration
AT binhu progressinthetreatmentofneovascularagerelatedmaculardegeneration