Reversible Effects of Exogenous GM3 on Meiotic Maturation and Cumulus Cells Expansion of Porcine Cumulus-oocyte Complexes

Reversible Effects of Exogenous GM3 on Meiotic Maturation and Cumulus Cells Expansion of Porcine Cumulus-oocyte Complexes

Ganglioside GM3 is known as an inhibition factor of cell differentiation and proliferation via inhibition of epidermal growth factor receptor (EGFR) phosphorylation. Our previous study showed that the exogenous ganglioside GM3 reduced the meiotic maturation of porcine oocytes and induced apoptosis a...

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Bibliographic Details
Main Authors: Jin-Woo Kim, Hyo-Jin Park, Jae-Min Jung, Seul-Gi Yang, Min-Ji Kim, In-Su Kim, Ho-Geun Jega, Deog-Bon Koo
Format: Article
Language:English
Published: The Korean Society of Animal Reproduction and Biotechnology 2018-12-01
Series:Journal of Animal Reproduction and Biotechnology
Subjects:
ganglioside gm3
oocytes maturation
egfr
apoptosis
pig
Online Access:http://www.e-jarb.org/journal/view.html?uid=72&vmd=Full

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