Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs

Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs

Summary: Sequencing of genes, such as BRCA1 and BRCA2, is recommended for individuals with a personal or family history of early onset and/or bilateral breast and/or ovarian cancer or a history of male breast cancer. Such sequencing efforts have resulted in the identification of more than 17,000 BRC...

Full description

Bibliographic Details
Main Authors: Kajal Biswas, Alexander Y. Mitrophanov, Sounak Sahu, Teresa Sullivan, Eileen Southon, Darryl Nousome, Susan Reid, Sakshi Narula, Julia Smolen, Trisha Sengupta, Maximilian Riedel-Topper, Medha Kapoor, Anav Babbar, Stacey Stauffer, Linda Cleveland, Mayank Tandon, Tyler Malys, Shyam K. Sharan
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports: Methods
Subjects:
CP: Cancer biology
CP: Genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237523002928

Internet

http://www.sciencedirect.com/science/article/pii/S2667237523002928

Similar Items