Polynomial Mendelian randomization reveals non-linear causal effects for obesity-related traits

Polynomial Mendelian randomization reveals non-linear causal effects for obesity-related traits

Causal inference is a critical step in improving our understanding of biological processes, and Mendelian randomization (MR) has emerged as one of the foremost methods to efficiently interrogate diverse hypotheses using large-scale, observational data from biobanks. Although many extensions have bee...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Jonathan Sulc, Jennifer Sjaarda, Zoltán Kutalik
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	Elsevier 2022-07-01
Cyfres:	HGG Advances
Pynciau:	genetics Mendelian randomization polynomial non-linear causal effects
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2666247722000409

Eitemau Tebyg

Causal roles of circulating cytokines in sarcopenia-related traits: a Mendelian randomization study
gan: Zhi Chen, et al.
Cyhoeddwyd: (2024-09-01)

Causal effects of psychiatric traits on the risk of urolithiasis in European and East Asian population: a Mendelian randomization analysis
gan: Qinhong Jiang, et al.
Cyhoeddwyd: (2024-08-01)

The causal relationship between obesity and IgA nephropathy: a Mendelian randomization study
gan: Peng-tao Dong, et al.
Cyhoeddwyd: (2024-05-01)

The Causal Effect of Obesity on the Risk of 15 Autoimmune Diseases: A Mendelian Randomization Study
gan: Xunliang Li, et al.
Cyhoeddwyd: (2023-10-01)

Causal associations between sleep traits and four cardiac diseases: a Mendelian randomization study
gan: Yongli Yang, et al.
Cyhoeddwyd: (2022-10-01)

Causal relationship between obesity and anorectal abscess: a Mendelian randomization study
gan: XiaoYu Zeng, et al.
Cyhoeddwyd: (2024-06-01)

Causal effects of socioeconomic traits on frailty: a Mendelian randomization study
gan: Jian Huang, et al.
Cyhoeddwyd: (2024-07-01)

Causal relationship between circulating lipid traits and periodontitis: univariable and multivariable Mendelian randomization
gan: Gaofu Hu, et al.
Cyhoeddwyd: (2023-07-01)

Mendelian randomization reveals no causal relationship between COVID‐19 susceptibility, hospitalization, or severity and epilepsy
gan: Zihua He, et al.
Cyhoeddwyd: (2023-12-01)

Causality between sleep traits and the risk of frailty: a Mendelian randomization study
gan: Zhen Deng, et al.
Cyhoeddwyd: (2024-05-01)

Causal Exposures in Pancreatic Cancer Incidence: Insights From Mendelian Randomization Studies
gan: Ashraf Mohamadkhani, et al.
Cyhoeddwyd: (2025-02-01)

Educational inequality in multimorbidity: causality and causal pathways. A mendelian randomisation study in UK Biobank
gan: Teri-Louise North, et al.
Cyhoeddwyd: (2023-08-01)

A two-sample Mendelian randomization study reveals the causal effects of statin medication on gut microbiota abundance in the European population
gan: Peng Zhou, et al.
Cyhoeddwyd: (2024-12-01)

Causality between ischemic stroke and epilepsy based on Mendelian randomization
gan: SHU Yun, et al.
Cyhoeddwyd: (2024-10-01)

Genetic prediction of the causal relationship between schizophrenia and tumors: a Mendelian randomized study
gan: Xintong Zhou, et al.
Cyhoeddwyd: (2024-02-01)

Causal Associations of Obesity With Achilles Tendinopathy: A Two-Sample Mendelian Randomization Study
gan: Lijuan He, et al.
Cyhoeddwyd: (2022-06-01)

Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study
gan: Shan-Shan Dong, et al.
Cyhoeddwyd: (2021-03-01)

Causal associations between sleep traits and brain structure: a bidirectional Mendelian randomization study
gan: Qiao Wang, et al.
Cyhoeddwyd: (2023-10-01)

Exploring the causal link among statin drugs and the osteoarthritis risk based on Mendelian randomization research
gan: Wenjie Chen, et al.
Cyhoeddwyd: (2024-09-01)

Causal associations of hypothyroidism with frozen shoulder: a two-sample bidirectional Mendelian randomization study
gan: Bin Chen, et al.
Cyhoeddwyd: (2024-09-01)

Causal Relationships Between Social Isolation and Osteoarthritis: A Mendelian Randomization Study in European Population
gan: Zheng C, et al.
Cyhoeddwyd: (2021-10-01)

Based on Mendelian Randomization to Explore the Causal Relationship with Insomnia and Gut Microbiota
gan: GUO Yumeng, CUI Yanglin, ZHANG Xianzhong
Cyhoeddwyd: (2025-03-01)

Causal association of immune cells and endometritis: a Mendelian randomization study
gan: Jing-wei Li, et al.
Cyhoeddwyd: (2024-10-01)

Assessment of causal effects of physical activity on the risk of osteoarthritis: a two-sample Mendelian randomization study
gan: Bin Wang, et al.
Cyhoeddwyd: (2023-10-01)

A causal association between obesity and constipation: a two-sample bidirectional Mendelian randomization study and meta-analysis
gan: Xian Sun, et al.
Cyhoeddwyd: (2024-11-01)

Causal relationship between physical activity and platelet traits: a Mendelian randomization study
gan: Mingyuan Jia, et al.
Cyhoeddwyd: (2024-03-01)

Mendelian randomization analysis reveals causal effects of migraine and its subtypes on early-onset ischemic stroke risk
gan: Rui Zhang, et al.
Cyhoeddwyd: (2024-12-01)

Bidirectional Two-Sample Mendelian Randomization Analysis Reveals Causal Associations Between Modifiable Risk Factors and Fibromyalgia
gan: Zu W, et al.
Cyhoeddwyd: (2024-10-01)

Causal Relationship Between Psoriasis and Bullous Pemphigoid: A Mendelian Randomization Analysis
gan: Xiaoxue Wang, et al.
Cyhoeddwyd: (2025-01-01)

Causal association between serum bilirubin and ischemic stroke: multivariable Mendelian randomization
gan: Jong Won Shin, et al.
Cyhoeddwyd: (2024-08-01)

The Causal Effect of Urate Level on Female Infertility: A Mendelian Randomization Study
gan: Jiawei Sun, et al.
Cyhoeddwyd: (2024-09-01)

Causal Relationship Between Micronutrient and Sleep Disorder: A Mendelian Randomization Study
gan: Jiang Y, et al.
Cyhoeddwyd: (2024-08-01)

Causal effect of gut microbiota and diabetic nephropathy: a Mendelian randomization study
gan: Ganyuan He, et al.
Cyhoeddwyd: (2024-04-01)

Causal associations between schizophrenia and cancers risk: a Mendelian randomization study
gan: Kai Zhou, et al.
Cyhoeddwyd: (2023-11-01)

Mendelian randomization analysis to analyze the genetic causality between different levels of obesity and different allergic diseases
gan: Yujian Li, et al.
Cyhoeddwyd: (2023-09-01)

Mendelian randomization analyses support causal relationship between gut microbiota and childhood obesity
gan: Qi Li, et al.
Cyhoeddwyd: (2023-08-01)

Mendelian Randomization Analysis Reveals Causal Associations of Polyunsaturated Fatty Acids with Sepsis and Mortality Risk
gan: Peipei Lei, et al.
Cyhoeddwyd: (2023-06-01)

Causal role of immune cells in uveitis: Mendelian randomization study
gan: Jiahui Wu, et al.
Cyhoeddwyd: (2024-07-01)

Mendelian randomization study on the causal relationship between food and cholelithiasis
gan: Zhicheng Liu, et al.
Cyhoeddwyd: (2024-03-01)

Causal relationship between insomnia and thyroid disease: A bidirectional Mendelian randomization study
gan: Zhonghui Li, et al.
Cyhoeddwyd: (2024-09-01)