Polynomial Mendelian randomization reveals non-linear causal effects for obesity-related traits

Causal inference is a critical step in improving our understanding of biological processes, and Mendelian randomization (MR) has emerged as one of the foremost methods to efficiently interrogate diverse hypotheses using large-scale, observational data from biobanks. Although many extensions have bee...

Полное описание

Библиографические подробности
Главные авторы: Jonathan Sulc, Jennifer Sjaarda, Zoltán Kutalik
Формат: Статья
Язык:English
Опубликовано: Elsevier 2022-07-01
Серии:HGG Advances
Предметы:
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2666247722000409