Diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsy

Abstract The diagnosis of pulmonary leiomyosarcoma using bronchoscopy is difficult, and surgical resection is often performed for definitive diagnosis and curative therapy. We report a case of pulmonary leiomyosarcoma, successfully diagnosed using repeated transbronchial cryobiopsy (TBCB). A 69‐year...

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Main Authors: Shinya Tsukamoto, Takamasa Kitajima, Satoshi Marumo, Motonari Fukui
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Respirology Case Reports
Subjects:
Online Access:https://doi.org/10.1002/rcr2.1078
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author Shinya Tsukamoto
Takamasa Kitajima
Satoshi Marumo
Motonari Fukui
author_facet Shinya Tsukamoto
Takamasa Kitajima
Satoshi Marumo
Motonari Fukui
author_sort Shinya Tsukamoto
collection DOAJ
description Abstract The diagnosis of pulmonary leiomyosarcoma using bronchoscopy is difficult, and surgical resection is often performed for definitive diagnosis and curative therapy. We report a case of pulmonary leiomyosarcoma, successfully diagnosed using repeated transbronchial cryobiopsy (TBCB). A 69‐year‐old‐woman was found to have an oval mass in the left hilar region extending into the left main bronchus on computed tomography (CT). All transbronchial biopsy specimens were necrotic, but repeated TBCB removed the necrotic tissue from the tumour and finally led to the diagnosis of pulmonary leiomyosarcoma. Proton therapy was administered, which caused shrinkage of the tumour. Thus, TBCB is useful for definitive diagnosis of leiomyosarcoma without surgical biopsy. Repeated TBCB can reduce tumour volume, eliminate atelectasis, and reduce the extent of radiotherapy exposure.
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spelling doaj.art-987c445d93294a0bac7fe25339c230bf2022-12-27T07:06:30ZengWileyRespirology Case Reports2051-33802023-01-01111n/an/a10.1002/rcr2.1078Diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsyShinya Tsukamoto0Takamasa Kitajima1Satoshi Marumo2Motonari Fukui3Respiratory Disease Center Tazuke Kofukai Medical Research Institute, Kitano Hospital Osaka JapanRespiratory Disease Center Tazuke Kofukai Medical Research Institute, Kitano Hospital Osaka JapanRespiratory Disease Center Tazuke Kofukai Medical Research Institute, Kitano Hospital Osaka JapanRespiratory Disease Center Tazuke Kofukai Medical Research Institute, Kitano Hospital Osaka JapanAbstract The diagnosis of pulmonary leiomyosarcoma using bronchoscopy is difficult, and surgical resection is often performed for definitive diagnosis and curative therapy. We report a case of pulmonary leiomyosarcoma, successfully diagnosed using repeated transbronchial cryobiopsy (TBCB). A 69‐year‐old‐woman was found to have an oval mass in the left hilar region extending into the left main bronchus on computed tomography (CT). All transbronchial biopsy specimens were necrotic, but repeated TBCB removed the necrotic tissue from the tumour and finally led to the diagnosis of pulmonary leiomyosarcoma. Proton therapy was administered, which caused shrinkage of the tumour. Thus, TBCB is useful for definitive diagnosis of leiomyosarcoma without surgical biopsy. Repeated TBCB can reduce tumour volume, eliminate atelectasis, and reduce the extent of radiotherapy exposure.https://doi.org/10.1002/rcr2.1078lung neoplasmsproton therapypulmonary leiomyosarcomatransbronchial biopsytransbronchial cryobiopsy
spellingShingle Shinya Tsukamoto
Takamasa Kitajima
Satoshi Marumo
Motonari Fukui
Diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsy
Respirology Case Reports
lung neoplasms
proton therapy
pulmonary leiomyosarcoma
transbronchial biopsy
transbronchial cryobiopsy
title Diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsy
title_full Diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsy
title_fullStr Diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsy
title_full_unstemmed Diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsy
title_short Diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsy
title_sort diagnosis of pulmonary leiomyosarcoma extending into the main bronchus using repeated transbronchial cryobiopsy
topic lung neoplasms
proton therapy
pulmonary leiomyosarcoma
transbronchial biopsy
transbronchial cryobiopsy
url https://doi.org/10.1002/rcr2.1078
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