An Overview of Recent Strategies in Pathogen Sensing

Pathogenic bacteria are one of the major concerns in food industries and water treatment facilities because of their rapid growth and deleterious effects on human health. The development of fast and accurate detection and identification systems for bacterial strains has long been an important issue...

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Main Authors: Jinseok Heo, Susan Z Hua
Format: Article
Language:English
Published: MDPI AG 2009-06-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/9/6/4483/
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author Jinseok Heo
Susan Z Hua
author_facet Jinseok Heo
Susan Z Hua
author_sort Jinseok Heo
collection DOAJ
description Pathogenic bacteria are one of the major concerns in food industries and water treatment facilities because of their rapid growth and deleterious effects on human health. The development of fast and accurate detection and identification systems for bacterial strains has long been an important issue to researchers. Although confirmative for the identification of bacteria, conventional methods require time-consuming process involving either the test of characteristic metabolites or cellular reproductive cycles. In this paper, we review recent sensing strategies based on micro- and nano-fabrication technology. These technologies allow for a great improvement of detection limit, therefore, reduce the time required for sample preparation. The paper will be focused on newly developed nano- and micro-scaled biosensors, novel sensing modalities utilizing microfluidic lab-on-a-chip, and array technology for the detection of pathogenic bacteria.
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spelling doaj.art-987f4ba065404dbb979623a2696d80302022-12-22T04:23:04ZengMDPI AGSensors1424-82202009-06-01964483450210.3390/s90604483An Overview of Recent Strategies in Pathogen SensingJinseok HeoSusan Z HuaPathogenic bacteria are one of the major concerns in food industries and water treatment facilities because of their rapid growth and deleterious effects on human health. The development of fast and accurate detection and identification systems for bacterial strains has long been an important issue to researchers. Although confirmative for the identification of bacteria, conventional methods require time-consuming process involving either the test of characteristic metabolites or cellular reproductive cycles. In this paper, we review recent sensing strategies based on micro- and nano-fabrication technology. These technologies allow for a great improvement of detection limit, therefore, reduce the time required for sample preparation. The paper will be focused on newly developed nano- and micro-scaled biosensors, novel sensing modalities utilizing microfluidic lab-on-a-chip, and array technology for the detection of pathogenic bacteria.http://www.mdpi.com/1424-8220/9/6/4483/pathogenmicrofabricationnanofabricationlab-on-a-chipmicrofluidics
spellingShingle Jinseok Heo
Susan Z Hua
An Overview of Recent Strategies in Pathogen Sensing
Sensors
pathogen
microfabrication
nanofabrication
lab-on-a-chip
microfluidics
title An Overview of Recent Strategies in Pathogen Sensing
title_full An Overview of Recent Strategies in Pathogen Sensing
title_fullStr An Overview of Recent Strategies in Pathogen Sensing
title_full_unstemmed An Overview of Recent Strategies in Pathogen Sensing
title_short An Overview of Recent Strategies in Pathogen Sensing
title_sort overview of recent strategies in pathogen sensing
topic pathogen
microfabrication
nanofabrication
lab-on-a-chip
microfluidics
url http://www.mdpi.com/1424-8220/9/6/4483/
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