Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety
A self-shielded medical cyclotron (11 MeV) was commissioned at our center, to produce positron emitters, namely, <sup> 18</sup> F, <sup> 15</sup> O, <sup> 13</sup> N and <sup> 11</sup> C for positron emission tomography (PET) imaging. Presently the cyc...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2007-01-01
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| Series: | Journal of Medical Physics |
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| Online Access: | http://www.jmp.org.in/article.asp?issn=0971-6203;year=2007;volume=32;issue=3;spage=118;epage=123;aulast=Pant |
| _version_ | 1818539753510797312 |
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| author | Pant G Senthamizhchelvan S |
| author_facet | Pant G Senthamizhchelvan S |
| author_sort | Pant G |
| collection | DOAJ |
| description | A self-shielded medical cyclotron (11 MeV) was commissioned at our center, to produce positron emitters, namely, <sup> 18</sup> F, <sup> 15</sup> O, <sup> 13</sup> N and <sup> 11</sup> C for positron emission tomography (PET) imaging. Presently the cyclotron has been exclusively used for the production of <sup> 18</sup> F<sup> -</sup> for <sup> 18</sup> F-FDG imaging. The operational parameters which influence the yield of <sup> 18</sup> F<sup> - </sup> production were monitored. The radiation levels in the cyclotron and radiochemistry laboratory were also monitored to assess the radiation safety status in the facility. The target material, <sup> 18</sup> O water, is bombarded with proton beam from the cyclotron to produce <sup> 18</sup> F<sup> -</sup> ion that is used for the synthesis of <sup> 18</sup> F-FDG. The operational parameters which influence the yield of <sup> 18</sup> F<sup> -</sup> were observed during 292 production runs out of a total of more than 400 runs. The radiation dose levels were also measured in the facility at various locations during cyclotron production runs and in the radiochemistry laboratory during <sup> 18</sup> F-FDG syntheses. It was observed that rinsing the target after delivery increased the number of production runs in a given target, as well as resulted in a better correlation between the duration of bombardment and the end of bombardment <sup> 18</sup> F<sup> -</sup> activity with absolutely clean target after being rebuilt. The radiation levels in the cyclotron and radiochemistry laboratory were observed to be well within prescribed limits with safe work practice. |
| first_indexed | 2024-12-11T21:46:16Z |
| format | Article |
| id | doaj.art-988065968edb486583ebc20bf788000c |
| institution | Directory Open Access Journal |
| issn | 0971-6203 |
| language | English |
| last_indexed | 2024-12-11T21:46:16Z |
| publishDate | 2007-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Medical Physics |
| spelling | doaj.art-988065968edb486583ebc20bf788000c2022-12-22T00:49:36ZengWolters Kluwer Medknow PublicationsJournal of Medical Physics0971-62032007-01-01323118123Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safetyPant GSenthamizhchelvan SA self-shielded medical cyclotron (11 MeV) was commissioned at our center, to produce positron emitters, namely, <sup> 18</sup> F, <sup> 15</sup> O, <sup> 13</sup> N and <sup> 11</sup> C for positron emission tomography (PET) imaging. Presently the cyclotron has been exclusively used for the production of <sup> 18</sup> F<sup> -</sup> for <sup> 18</sup> F-FDG imaging. The operational parameters which influence the yield of <sup> 18</sup> F<sup> - </sup> production were monitored. The radiation levels in the cyclotron and radiochemistry laboratory were also monitored to assess the radiation safety status in the facility. The target material, <sup> 18</sup> O water, is bombarded with proton beam from the cyclotron to produce <sup> 18</sup> F<sup> -</sup> ion that is used for the synthesis of <sup> 18</sup> F-FDG. The operational parameters which influence the yield of <sup> 18</sup> F<sup> -</sup> were observed during 292 production runs out of a total of more than 400 runs. The radiation dose levels were also measured in the facility at various locations during cyclotron production runs and in the radiochemistry laboratory during <sup> 18</sup> F-FDG syntheses. It was observed that rinsing the target after delivery increased the number of production runs in a given target, as well as resulted in a better correlation between the duration of bombardment and the end of bombardment <sup> 18</sup> F<sup> -</sup> activity with absolutely clean target after being rebuilt. The radiation levels in the cyclotron and radiochemistry laboratory were observed to be well within prescribed limits with safe work practice.http://www.jmp.org.in/article.asp?issn=0971-6203;year=2007;volume=32;issue=3;spage=118;epage=123;aulast=Pant<sup>18</sup> F-FDGradiation monitoringself-shielded cyclotron |
| spellingShingle | Pant G Senthamizhchelvan S Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety Journal of Medical Physics <sup>18</sup> F-FDG radiation monitoring self-shielded cyclotron |
| title | Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety |
| title_full | Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety |
| title_fullStr | Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety |
| title_full_unstemmed | Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety |
| title_short | Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety |
| title_sort | initial experience with an 11 mev self shielded medical cyclotron on operation and radiation safety |
| topic | <sup>18</sup> F-FDG radiation monitoring self-shielded cyclotron |
| url | http://www.jmp.org.in/article.asp?issn=0971-6203;year=2007;volume=32;issue=3;spage=118;epage=123;aulast=Pant |
| work_keys_str_mv | AT pantg initialexperiencewithan11mevselfshieldedmedicalcyclotrononoperationandradiationsafety AT senthamizhchelvans initialexperiencewithan11mevselfshieldedmedicalcyclotrononoperationandradiationsafety |