Common Adverse drug reactions to First line drugs in Tuberculosis care and the role of m-Health in patient self-reporting and pharmacovigilance in Nigeria: A Narrative review

The treatment of tuberculosis requires the use of First line drugs that often cause adverse drug reactions (ADR) in some patients and this is capable of affecting adherence to the treatment. Many patients do not report these ADRs even though technologies are available at their disposal. The objecti...

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Main Authors: Edward E, Ekanem US, Ekanem AM
Format: Article
Language:English
Published: Nigerian Medical Association, Akwa Ibom State Branch 2021-04-01
Series:Ibom Medical Journal
Subjects:
Online Access:https://ibommedicaljournal.org/index.php/imjhome/article/view/70
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author Edward E
Ekanem US
Ekanem AM
author_facet Edward E
Ekanem US
Ekanem AM
author_sort Edward E
collection DOAJ
description The treatment of tuberculosis requires the use of First line drugs that often cause adverse drug reactions (ADR) in some patients and this is capable of affecting adherence to the treatment. Many patients do not report these ADRs even though technologies are available at their disposal. The objectives of this review are to assess the common adverse drug reactions reported during the care of patients on First line anti-TB drugs and the use of m-health in self-reporting the ADRs by patients receiving anti-TB care. A literature search was conducted using key words on PUBMED and GOOGLE SCHOLAR. The commonest ADRs many patients presented with were gastrointestinal symptoms and symptoms of drug induced hepatotoxicity. The use of m-Health as an intervention for reporting ADRs is poor in sub-Saharan Africa, however in spite of some challenges, it is seen as a veritable opportunity for patient reporting of ADRs and the improvement of outcomes of Directly Observed Therapy Short course, (DOTS) for tuberculosis management.
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spelling doaj.art-9880d31b82044e019e6bec6e381b55682024-03-06T12:03:26ZengNigerian Medical Association, Akwa Ibom State BranchIbom Medical Journal1597-71882735-99642021-04-0114210.61386/imj.v14i2.70Common Adverse drug reactions to First line drugs in Tuberculosis care and the role of m-Health in patient self-reporting and pharmacovigilance in Nigeria: A Narrative reviewEdward E0Ekanem USEkanem AMDepartment of Community Health, University of Uyo Teaching Hospital, Uyo Akwa Ibom State, Nigeria The treatment of tuberculosis requires the use of First line drugs that often cause adverse drug reactions (ADR) in some patients and this is capable of affecting adherence to the treatment. Many patients do not report these ADRs even though technologies are available at their disposal. The objectives of this review are to assess the common adverse drug reactions reported during the care of patients on First line anti-TB drugs and the use of m-health in self-reporting the ADRs by patients receiving anti-TB care. A literature search was conducted using key words on PUBMED and GOOGLE SCHOLAR. The commonest ADRs many patients presented with were gastrointestinal symptoms and symptoms of drug induced hepatotoxicity. The use of m-Health as an intervention for reporting ADRs is poor in sub-Saharan Africa, however in spite of some challenges, it is seen as a veritable opportunity for patient reporting of ADRs and the improvement of outcomes of Directly Observed Therapy Short course, (DOTS) for tuberculosis management. https://ibommedicaljournal.org/index.php/imjhome/article/view/70TuberculosisFirst line drugsAdverse drug reactionsHealthPatient self-reporting
spellingShingle Edward E
Ekanem US
Ekanem AM
Common Adverse drug reactions to First line drugs in Tuberculosis care and the role of m-Health in patient self-reporting and pharmacovigilance in Nigeria: A Narrative review
Ibom Medical Journal
Tuberculosis
First line drugs
Adverse drug reactions
Health
Patient self-reporting
title Common Adverse drug reactions to First line drugs in Tuberculosis care and the role of m-Health in patient self-reporting and pharmacovigilance in Nigeria: A Narrative review
title_full Common Adverse drug reactions to First line drugs in Tuberculosis care and the role of m-Health in patient self-reporting and pharmacovigilance in Nigeria: A Narrative review
title_fullStr Common Adverse drug reactions to First line drugs in Tuberculosis care and the role of m-Health in patient self-reporting and pharmacovigilance in Nigeria: A Narrative review
title_full_unstemmed Common Adverse drug reactions to First line drugs in Tuberculosis care and the role of m-Health in patient self-reporting and pharmacovigilance in Nigeria: A Narrative review
title_short Common Adverse drug reactions to First line drugs in Tuberculosis care and the role of m-Health in patient self-reporting and pharmacovigilance in Nigeria: A Narrative review
title_sort common adverse drug reactions to first line drugs in tuberculosis care and the role of m health in patient self reporting and pharmacovigilance in nigeria a narrative review
topic Tuberculosis
First line drugs
Adverse drug reactions
Health
Patient self-reporting
url https://ibommedicaljournal.org/index.php/imjhome/article/view/70
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