Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus

In experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclo...

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Main Authors: Ye. A. Safonova, K. A. Lopatina, T. V. Vetoshkina, A. M. Guriyev, T. G. Razina, Ye. P. Zuyeva
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2011-02-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/1318
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author Ye. A. Safonova
K. A. Lopatina
T. V. Vetoshkina
A. M. Guriyev
T. G. Razina
Ye. P. Zuyeva
author_facet Ye. A. Safonova
K. A. Lopatina
T. V. Vetoshkina
A. M. Guriyev
T. G. Razina
Ye. P. Zuyeva
author_sort Ye. A. Safonova
collection DOAJ
description In experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclophosphamide damaged liver, as well as increase the antimetastatic effect of cytostatics. Water-soluble polysaccharides from Acorus calamus restore most efficiently biochemical disturbances at cyclophosphamide intoxication.
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spelling doaj.art-98822fbbbfc849d484c758537074fa5e2023-03-13T09:58:14ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-02-01101707510.20538/1682-0363-2011-1-70-75841Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamusYe. A. Safonova0K. A. Lopatina1T. V. Vetoshkina2A. M. Guriyev3T. G. Razina4Ye. P. Zuyeva5НИИ фармакологии СО РАМННИИ фармакологии СО РАМННИИ фармакологии СО РАМНСибирский государственный медицинский университетНИИ фармакологии СО РАМННИИ фармакологии СО РАМНIn experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclophosphamide damaged liver, as well as increase the antimetastatic effect of cytostatics. Water-soluble polysaccharides from Acorus calamus restore most efficiently biochemical disturbances at cyclophosphamide intoxication.https://bulletin.ssmu.ru/jour/article/view/1318полисахаридыциклофосфанферменты печени
spellingShingle Ye. A. Safonova
K. A. Lopatina
T. V. Vetoshkina
A. M. Guriyev
T. G. Razina
Ye. P. Zuyeva
Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus
Бюллетень сибирской медицины
полисахариды
циклофосфан
ферменты печени
title Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus
title_full Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus
title_fullStr Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus
title_full_unstemmed Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus
title_short Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus
title_sort correction of cyclophosphan hepatotoxicity by water soluble polysaccharides from tussilago farfara and acorus calamus
topic полисахариды
циклофосфан
ферменты печени
url https://bulletin.ssmu.ru/jour/article/view/1318
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