Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus
In experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclo...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Siberian State Medical University (Tomsk)
2011-02-01
|
Series: | Бюллетень сибирской медицины |
Subjects: | |
Online Access: | https://bulletin.ssmu.ru/jour/article/view/1318 |
_version_ | 1827991735655989248 |
---|---|
author | Ye. A. Safonova K. A. Lopatina T. V. Vetoshkina A. M. Guriyev T. G. Razina Ye. P. Zuyeva |
author_facet | Ye. A. Safonova K. A. Lopatina T. V. Vetoshkina A. M. Guriyev T. G. Razina Ye. P. Zuyeva |
author_sort | Ye. A. Safonova |
collection | DOAJ |
description | In experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclophosphamide damaged liver, as well as increase the antimetastatic effect of cytostatics. Water-soluble polysaccharides from Acorus calamus restore most efficiently biochemical disturbances at cyclophosphamide intoxication. |
first_indexed | 2024-04-10T01:10:00Z |
format | Article |
id | doaj.art-98822fbbbfc849d484c758537074fa5e |
institution | Directory Open Access Journal |
issn | 1682-0363 1819-3684 |
language | English |
last_indexed | 2024-04-10T01:10:00Z |
publishDate | 2011-02-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj.art-98822fbbbfc849d484c758537074fa5e2023-03-13T09:58:14ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-02-01101707510.20538/1682-0363-2011-1-70-75841Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamusYe. A. Safonova0K. A. Lopatina1T. V. Vetoshkina2A. M. Guriyev3T. G. Razina4Ye. P. Zuyeva5НИИ фармакологии СО РАМННИИ фармакологии СО РАМННИИ фармакологии СО РАМНСибирский государственный медицинский университетНИИ фармакологии СО РАМННИИ фармакологии СО РАМНIn experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclophosphamide damaged liver, as well as increase the antimetastatic effect of cytostatics. Water-soluble polysaccharides from Acorus calamus restore most efficiently biochemical disturbances at cyclophosphamide intoxication.https://bulletin.ssmu.ru/jour/article/view/1318полисахаридыциклофосфанферменты печени |
spellingShingle | Ye. A. Safonova K. A. Lopatina T. V. Vetoshkina A. M. Guriyev T. G. Razina Ye. P. Zuyeva Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus Бюллетень сибирской медицины полисахариды циклофосфан ферменты печени |
title | Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus |
title_full | Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus |
title_fullStr | Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus |
title_full_unstemmed | Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus |
title_short | Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus |
title_sort | correction of cyclophosphan hepatotoxicity by water soluble polysaccharides from tussilago farfara and acorus calamus |
topic | полисахариды циклофосфан ферменты печени |
url | https://bulletin.ssmu.ru/jour/article/view/1318 |
work_keys_str_mv | AT yeasafonova correctionofcyclophosphanhepatotoxicitybywatersolublepolysaccharidesfromtussilagofarfaraandacoruscalamus AT kalopatina correctionofcyclophosphanhepatotoxicitybywatersolublepolysaccharidesfromtussilagofarfaraandacoruscalamus AT tvvetoshkina correctionofcyclophosphanhepatotoxicitybywatersolublepolysaccharidesfromtussilagofarfaraandacoruscalamus AT amguriyev correctionofcyclophosphanhepatotoxicitybywatersolublepolysaccharidesfromtussilagofarfaraandacoruscalamus AT tgrazina correctionofcyclophosphanhepatotoxicitybywatersolublepolysaccharidesfromtussilagofarfaraandacoruscalamus AT yepzuyeva correctionofcyclophosphanhepatotoxicitybywatersolublepolysaccharidesfromtussilagofarfaraandacoruscalamus |