Improving access to HbA1c in sub-Saharan Africa (IA3) cohort: cohort profile

INTRODUCTION: Glycated haemoglobin (HbA1c) is the best surrogate of average blood glucose control in diabetic patients, and lowering HbA1c significantly reduces diabetes complications. Moreover, immediate feedback of HbA1c measurement to patients may improve control. However, HbA1c is unavailable in...

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Main Authors: Naby Balde, Alioune Camara, Joelle Sobngwi-Tambekou, Eric Balti, Alain Tchatchoua, Leopold Fezeu, Serge Limen, Sylvie Ngamani, Suzanne Ngapout, Andre Kengne, Eugene Sobngwi
Format: Article
Language:English
Published: The Pan African Medical Journal 2017-08-01
Series:The Pan African Medical Journal
Subjects:
Online Access: https://www.panafrican-med-journal.com/content/article/27/275/pdf/275.pdf
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author Naby Balde
Alioune Camara
Joelle Sobngwi-Tambekou
Eric Balti
Alain Tchatchoua
Leopold Fezeu
Serge Limen
Sylvie Ngamani
Suzanne Ngapout
Andre Kengne
Eugene Sobngwi
author_facet Naby Balde
Alioune Camara
Joelle Sobngwi-Tambekou
Eric Balti
Alain Tchatchoua
Leopold Fezeu
Serge Limen
Sylvie Ngamani
Suzanne Ngapout
Andre Kengne
Eugene Sobngwi
author_sort Naby Balde
collection DOAJ
description INTRODUCTION: Glycated haemoglobin (HbA1c) is the best surrogate of average blood glucose control in diabetic patients, and lowering HbA1c significantly reduces diabetes complications. Moreover, immediate feedback of HbA1c measurement to patients may improve control. However, HbA1c is unavailable in most parts of Africa, a continent with one of the highest burden of diabetes. To translate these evidences, we are conducting a multicentric project in 10 health care facilities in Guinea and Cameroon to evaluate the feasibility and one-year benefit of affordable HbA1c measurement with immediate feedback to patients on diabetes control and related outcomes. PARTICIPANTS: we consecutively enrolled patients with diabetes mellitus independently of the type of disease. We hypothesised an average 1%-decrease in HbA1c in a 1000-patient study population, with a 20% increase in the number of patients reaching treatment goals within 12 months of intervention and follow-up. FINDINGS TO DATE: a total of 1, 349 diabetic patients aged 56.2,12.6 years were enrolled (813 in Cameroon and 536 in Guinea) of whom 59.8% are women. The mean duration of diabetes was 7.4,6.3 years and baseline HbA1c was 9.7,2.6% in Guinea and 8.6,2.5% in Cameroon. FUTURE PLANS: to investigate whether the introduction of routine HbA1c measurement with immediate feedback to patients and provision of relevant education would improve diabetes control after one year. The impact of the intervention on diabetes associated-complications and mortality warrant further assessment in the long term.
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spelling doaj.art-988530aa954f4cb5b8c4a4d396e5f5e32022-12-21T18:41:21ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882017-08-012727510.11604/pamj.2017.27.275.1027010270Improving access to HbA1c in sub-Saharan Africa (IA3) cohort: cohort profileNaby Balde0Alioune Camara1Joelle Sobngwi-Tambekou2Eric Balti3Alain Tchatchoua4Leopold Fezeu5Serge Limen6Sylvie Ngamani7Suzanne Ngapout8Andre Kengne9Eugene Sobngwi10 University Hospital Donka, Conakry, Guinea University Hospital Donka, Conakry, Guinea Catholic University of Central Africa, Yaoundé, Cameroon Recherche Santé Développement, Yaoundé, Cameroon Recherche Santé Développement, Yaoundé, Cameroon University of Paris 13, Paris, France Recherche Santé Développement, Yaoundé, Cameroon Recherche Santé Développement, Yaoundé, Cameroon Recherche Santé Développement, Yaoundé, Cameroon South African Medical Research Council and University of Cape Town, Cape Town, South Africa Recherche Santé Développement, Yaoundé, Cameroon INTRODUCTION: Glycated haemoglobin (HbA1c) is the best surrogate of average blood glucose control in diabetic patients, and lowering HbA1c significantly reduces diabetes complications. Moreover, immediate feedback of HbA1c measurement to patients may improve control. However, HbA1c is unavailable in most parts of Africa, a continent with one of the highest burden of diabetes. To translate these evidences, we are conducting a multicentric project in 10 health care facilities in Guinea and Cameroon to evaluate the feasibility and one-year benefit of affordable HbA1c measurement with immediate feedback to patients on diabetes control and related outcomes. PARTICIPANTS: we consecutively enrolled patients with diabetes mellitus independently of the type of disease. We hypothesised an average 1%-decrease in HbA1c in a 1000-patient study population, with a 20% increase in the number of patients reaching treatment goals within 12 months of intervention and follow-up. FINDINGS TO DATE: a total of 1, 349 diabetic patients aged 56.2,12.6 years were enrolled (813 in Cameroon and 536 in Guinea) of whom 59.8% are women. The mean duration of diabetes was 7.4,6.3 years and baseline HbA1c was 9.7,2.6% in Guinea and 8.6,2.5% in Cameroon. FUTURE PLANS: to investigate whether the introduction of routine HbA1c measurement with immediate feedback to patients and provision of relevant education would improve diabetes control after one year. The impact of the intervention on diabetes associated-complications and mortality warrant further assessment in the long term. https://www.panafrican-med-journal.com/content/article/27/275/pdf/275.pdf diabetes mellitushba1cdiabetes controlcomplicationsmortality
spellingShingle Naby Balde
Alioune Camara
Joelle Sobngwi-Tambekou
Eric Balti
Alain Tchatchoua
Leopold Fezeu
Serge Limen
Sylvie Ngamani
Suzanne Ngapout
Andre Kengne
Eugene Sobngwi
Improving access to HbA1c in sub-Saharan Africa (IA3) cohort: cohort profile
The Pan African Medical Journal
diabetes mellitus
hba1c
diabetes control
complications
mortality
title Improving access to HbA1c in sub-Saharan Africa (IA3) cohort: cohort profile
title_full Improving access to HbA1c in sub-Saharan Africa (IA3) cohort: cohort profile
title_fullStr Improving access to HbA1c in sub-Saharan Africa (IA3) cohort: cohort profile
title_full_unstemmed Improving access to HbA1c in sub-Saharan Africa (IA3) cohort: cohort profile
title_short Improving access to HbA1c in sub-Saharan Africa (IA3) cohort: cohort profile
title_sort improving access to hba1c in sub saharan africa ia3 cohort cohort profile
topic diabetes mellitus
hba1c
diabetes control
complications
mortality
url https://www.panafrican-med-journal.com/content/article/27/275/pdf/275.pdf
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