Sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers: A longitudinal paired study
BackgroundMany countries have currently relied on various types of vaccines for the public to control the coronavirus disease 2019 (COVID-19) pandemic. The adverse reactions (ARs) after vaccination may affect vaccination coverage and confidence. However, whether sleep quality was associated with ARs...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Behavioral Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnbeh.2022.867650/full |
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| author | Ning Xiao Xingli Xu Zhiyue Ma Xiaoxu Yu Yong Feng Bilan Li Yuping Liu Gang He Jiangang Fan Bin Li Xiaolong Zhao |
| author_facet | Ning Xiao Xingli Xu Zhiyue Ma Xiaoxu Yu Yong Feng Bilan Li Yuping Liu Gang He Jiangang Fan Bin Li Xiaolong Zhao |
| author_sort | Ning Xiao |
| collection | DOAJ |
| description | BackgroundMany countries have currently relied on various types of vaccines for the public to control the coronavirus disease 2019 (COVID-19) pandemic. The adverse reactions (ARs) after vaccination may affect vaccination coverage and confidence. However, whether sleep quality was associated with ARs after vaccination remains unclear.MethodsWe designed a longitudinal paired study within a hospital setting. We collected data about the side effects within 7 days after two doses of scheduled vaccination among healthcare workers (HCWs). All HCWs were asked to complete a sleep survey indexed by the Pittsburgh Sleep Quality Index (PSQI) before vaccination and after a 1-month follow-up. Then, we explored the relationship between sleep quality before or after vaccination and the occurrence of ARs.ResultsA total of 345 HCWs were recruited to receive COVID-19 vaccination. The sleep quality became worse after vaccination. All local and systemic reactions were mild or moderate in severity (32.46%), and no serious adverse event was reported. Binary logistic regression showed participants with poor sleep quality (PSQI > 5) than good sleep quality (PSQI ≤ 5) before the two doses of vaccination, respectively, exhibited 1.515 and 1.107 times risk of ARs after each vaccination (both p < 0.001).ConclusionThere is an apparently complex bidirectional relationship between sleep quality and COVID-19 vaccination adverse effects. Poor sleep quality significantly increases the risk of mild ARs after vaccination, while vaccination may cause a temporary decline in sleep quality. |
| first_indexed | 2024-04-11T01:04:29Z |
| format | Article |
| id | doaj.art-9888b04588c84f4089e3a8237f190fcb |
| institution | Directory Open Access Journal |
| issn | 1662-5153 |
| language | English |
| last_indexed | 2024-04-11T01:04:29Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Behavioral Neuroscience |
| spelling | doaj.art-9888b04588c84f4089e3a8237f190fcb2023-01-04T14:19:42ZengFrontiers Media S.A.Frontiers in Behavioral Neuroscience1662-51532023-01-011610.3389/fnbeh.2022.867650867650Sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers: A longitudinal paired studyNing Xiao0Xingli Xu1Zhiyue Ma2Xiaoxu Yu3Yong Feng4Bilan Li5Yuping Liu6Gang He7Jiangang Fan8Bin Li9Xiaolong Zhao10Department of Health Management Center and Institute of Health Management, Sichuan Provincial People’s Hospital, Chengdu, ChinaUltrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Health Management Center and Institute of Health Management, Sichuan Provincial People’s Hospital, Chengdu, ChinaDepartment of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaBackgroundMany countries have currently relied on various types of vaccines for the public to control the coronavirus disease 2019 (COVID-19) pandemic. The adverse reactions (ARs) after vaccination may affect vaccination coverage and confidence. However, whether sleep quality was associated with ARs after vaccination remains unclear.MethodsWe designed a longitudinal paired study within a hospital setting. We collected data about the side effects within 7 days after two doses of scheduled vaccination among healthcare workers (HCWs). All HCWs were asked to complete a sleep survey indexed by the Pittsburgh Sleep Quality Index (PSQI) before vaccination and after a 1-month follow-up. Then, we explored the relationship between sleep quality before or after vaccination and the occurrence of ARs.ResultsA total of 345 HCWs were recruited to receive COVID-19 vaccination. The sleep quality became worse after vaccination. All local and systemic reactions were mild or moderate in severity (32.46%), and no serious adverse event was reported. Binary logistic regression showed participants with poor sleep quality (PSQI > 5) than good sleep quality (PSQI ≤ 5) before the two doses of vaccination, respectively, exhibited 1.515 and 1.107 times risk of ARs after each vaccination (both p < 0.001).ConclusionThere is an apparently complex bidirectional relationship between sleep quality and COVID-19 vaccination adverse effects. Poor sleep quality significantly increases the risk of mild ARs after vaccination, while vaccination may cause a temporary decline in sleep quality.https://www.frontiersin.org/articles/10.3389/fnbeh.2022.867650/fullCOVID-19vaccinesleep disorderadverse reactionshealthcare workers |
| spellingShingle | Ning Xiao Xingli Xu Zhiyue Ma Xiaoxu Yu Yong Feng Bilan Li Yuping Liu Gang He Jiangang Fan Bin Li Xiaolong Zhao Sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers: A longitudinal paired study Frontiers in Behavioral Neuroscience COVID-19 vaccine sleep disorder adverse reactions healthcare workers |
| title | Sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers: A longitudinal paired study |
| title_full | Sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers: A longitudinal paired study |
| title_fullStr | Sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers: A longitudinal paired study |
| title_full_unstemmed | Sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers: A longitudinal paired study |
| title_short | Sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers: A longitudinal paired study |
| title_sort | sleep quality was associated with adverse reactions after coronavirus disease 2019 vaccination among healthcare workers a longitudinal paired study |
| topic | COVID-19 vaccine sleep disorder adverse reactions healthcare workers |
| url | https://www.frontiersin.org/articles/10.3389/fnbeh.2022.867650/full |
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