Association between serum levels of caspase-cleaved cytokeratin-18 and early mortality in patients with severe spontaneous intracerebral hemorrhage

Association between serum levels of caspase-cleaved cytokeratin-18 and early mortality in patients with severe spontaneous intracerebral hemorrhage

Abstract Background Apoptotic changes after cerebral hemorrhage in brain samples of humans have been found. Caspase-cleaved cytokeratin (CCCK)-18 could be detected in the bloodstream during apoptosis. Higher circulating CCCK-18 levels have been associated with 6-month mortality in patients with basa...

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Bibliographic Details
Main Authors: Leonardo Lorente, María M. Martín, Antonia Pérez-Cejas, Luis Ramos, Mónica Argueso, Jordi Solé-Violán, Juan J. Cáceres, Alejandro Jiménez, Victor García-Marín
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Neuroscience
Subjects:
Caspase-cleaved cytokeratin-18
Spontaneous intracerebral hemorrhage
Patients
Mortality
Online Access:http://link.springer.com/article/10.1186/s12868-018-0424-1

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