Implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgery
Patients undergoing neurosurgery are predisposed to a variety of complications related to mechanical ventilation (MV). There is an increased incidence of extubation failure, pneumonia, and prolonged MV among such patients. The aim of the present study was to assess the influence of extubation failur...
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| Format: | Article |
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Associação Brasileira de Divulgação Científica
2011-12-01
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| Series: | Brazilian Journal of Medical and Biological Research |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001200014 |
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| author | M.C. Vidotto L.C. Sogame M.R. Gazzotti M. Prandini J.R. Jardim |
| author_facet | M.C. Vidotto L.C. Sogame M.R. Gazzotti M. Prandini J.R. Jardim |
| author_sort | M.C. Vidotto |
| collection | DOAJ |
| description | Patients undergoing neurosurgery are predisposed to a variety of complications related to mechanical ventilation (MV). There is an increased incidence of extubation failure, pneumonia, and prolonged MV among such patients. The aim of the present study was to assess the influence of extubation failure and prolonged MV on the following variables: postoperative pulmonary complications (PPC), mortality, reoperation, tracheostomy, and duration of postoperative hospitalization following elective intra-cranial surgery. The study involved a prospective observational cohort of 317 patients submitted to elective intracranial surgery for tumors, aneurysms and arteriovenous malformation. Preoperative assessment was performed and patients were followed up for the determination of extubation failure and prolonged MV (>48 h) until discharge from the hospital or death. The occurrence of PPC, incidence of death, the need for reoperation and tracheostomy, and the length of hospitalization were assessed during the postoperative period. Twenty-six patients (8.2%) experienced extubation failure and 30 (9.5%) needed prolonged MV after surgery. Multivariate analysis showed that extubation failure was significant for the occurrence of death (OR = 8.05 [1.88; 34.36]), PPC (OR = 11.18 [2.27; 55.02]) and tracheostomy (OR = 7.8 [1.12; 55.07]). Prolonged MV was significant only for the occurrence of PPC (OR = 4.87 [1.3; 18.18]). Elective intracranial surgery patients who experienced extubation failure or required prolonged MV had a higher incidence of PPC, reoperation and tracheostomy and required a longer period of time in the ICU. Level of consciousness and extubation failure were associated with death and PPC. Patients who required prolonged MV had a higher incidence of extubation failure. |
| first_indexed | 2024-12-11T17:16:31Z |
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| id | doaj.art-9894a458b806457bb59782541135d18e |
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| issn | 0100-879X 1414-431X |
| language | English |
| last_indexed | 2024-12-11T17:16:31Z |
| publishDate | 2011-12-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-9894a458b806457bb59782541135d18e2022-12-22T00:57:18ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research0100-879X1414-431X2011-12-01441212911298Implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgeryM.C. VidottoL.C. SogameM.R. GazzottiM. PrandiniJ.R. JardimPatients undergoing neurosurgery are predisposed to a variety of complications related to mechanical ventilation (MV). There is an increased incidence of extubation failure, pneumonia, and prolonged MV among such patients. The aim of the present study was to assess the influence of extubation failure and prolonged MV on the following variables: postoperative pulmonary complications (PPC), mortality, reoperation, tracheostomy, and duration of postoperative hospitalization following elective intra-cranial surgery. The study involved a prospective observational cohort of 317 patients submitted to elective intracranial surgery for tumors, aneurysms and arteriovenous malformation. Preoperative assessment was performed and patients were followed up for the determination of extubation failure and prolonged MV (>48 h) until discharge from the hospital or death. The occurrence of PPC, incidence of death, the need for reoperation and tracheostomy, and the length of hospitalization were assessed during the postoperative period. Twenty-six patients (8.2%) experienced extubation failure and 30 (9.5%) needed prolonged MV after surgery. Multivariate analysis showed that extubation failure was significant for the occurrence of death (OR = 8.05 [1.88; 34.36]), PPC (OR = 11.18 [2.27; 55.02]) and tracheostomy (OR = 7.8 [1.12; 55.07]). Prolonged MV was significant only for the occurrence of PPC (OR = 4.87 [1.3; 18.18]). Elective intracranial surgery patients who experienced extubation failure or required prolonged MV had a higher incidence of PPC, reoperation and tracheostomy and required a longer period of time in the ICU. Level of consciousness and extubation failure were associated with death and PPC. Patients who required prolonged MV had a higher incidence of extubation failure.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001200014NeurosurgeryCraniotomyVentilator weaningIntratracheal intubationPostoperative period |
| spellingShingle | M.C. Vidotto L.C. Sogame M.R. Gazzotti M. Prandini J.R. Jardim Implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgery Brazilian Journal of Medical and Biological Research Neurosurgery Craniotomy Ventilator weaning Intratracheal intubation Postoperative period |
| title | Implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgery |
| title_full | Implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgery |
| title_fullStr | Implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgery |
| title_full_unstemmed | Implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgery |
| title_short | Implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgery |
| title_sort | implications of extubation failure and prolonged mechanical ventilation in the postoperative period following elective intracranial surgery |
| topic | Neurosurgery Craniotomy Ventilator weaning Intratracheal intubation Postoperative period |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001200014 |
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