Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameter

ABSTRACT Purpose: The aim of this study was to evaluate the relationship between tumor size and grade with visceral adipose index (VAI) levels in patients with renal cell carcinoma. Materials and methods: We retrospectively reviewed the records of 310 consecutive patients with RCC who underwent ra...

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Main Authors: Alper Otunctemur, Murat Dursun, Kutan Ozer, Ozan Horsanali, Emin Ozbek
Format: Article
Language:English
Published: Sociedade Brasileira de Urologia
Series:International Brazilian Journal of Urology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000500955&lng=en&tlng=en
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author Alper Otunctemur
Murat Dursun
Kutan Ozer
Ozan Horsanali
Emin Ozbek
author_facet Alper Otunctemur
Murat Dursun
Kutan Ozer
Ozan Horsanali
Emin Ozbek
author_sort Alper Otunctemur
collection DOAJ
description ABSTRACT Purpose: The aim of this study was to evaluate the relationship between tumor size and grade with visceral adipose index (VAI) levels in patients with renal cell carcinoma. Materials and methods: We retrospectively reviewed the records of 310 consecutive patients with RCC who underwent radical nephrectomy at our institution between January 2007 and May 2014. VAI was calculates for males and females seperately as this formula like previous study. The relationship between tumor size and nuclear grade with VAI levels were evaluated statisticaly. Analyses were completed using Chi-square tests and Logistic regression analysis. Results: Among the 310 total patients analyzed in our study, there were 176 males (56.8%) and 134 females (43.2%). VAI levels were statistically higher in men and women with high tumor size (p<0.001). VAI levels were statistically higher in men and women with high fuhrman grade (p<0.001). Conclusions: The components of VAI may have effect on tumor carcinogenesis in similar pathways. In our study patients with high VAI levels were found to have statistically significant higher nuclear grade and tumor size. VAI can be a useful index for the evaluation and calculation of renal cell cancer aggressiviness. Further studies with more patients are needed to confirm our study.
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spelling doaj.art-98955dd1959047b1ae8ecac9e56151e92022-12-21T23:52:37ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-611942595595910.1590/S1677-5538.IBJU.2015.0396S1677-55382016000500955Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameterAlper OtunctemurMurat DursunKutan OzerOzan HorsanaliEmin OzbekABSTRACT Purpose: The aim of this study was to evaluate the relationship between tumor size and grade with visceral adipose index (VAI) levels in patients with renal cell carcinoma. Materials and methods: We retrospectively reviewed the records of 310 consecutive patients with RCC who underwent radical nephrectomy at our institution between January 2007 and May 2014. VAI was calculates for males and females seperately as this formula like previous study. The relationship between tumor size and nuclear grade with VAI levels were evaluated statisticaly. Analyses were completed using Chi-square tests and Logistic regression analysis. Results: Among the 310 total patients analyzed in our study, there were 176 males (56.8%) and 134 females (43.2%). VAI levels were statistically higher in men and women with high tumor size (p<0.001). VAI levels were statistically higher in men and women with high fuhrman grade (p<0.001). Conclusions: The components of VAI may have effect on tumor carcinogenesis in similar pathways. In our study patients with high VAI levels were found to have statistically significant higher nuclear grade and tumor size. VAI can be a useful index for the evaluation and calculation of renal cell cancer aggressiviness. Further studies with more patients are needed to confirm our study.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000500955&lng=en&tlng=enCarcinomaRenal CellVisceral PainHypertensionBody Mass Index
spellingShingle Alper Otunctemur
Murat Dursun
Kutan Ozer
Ozan Horsanali
Emin Ozbek
Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameter
International Brazilian Journal of Urology
Carcinoma
Renal Cell
Visceral Pain
Hypertension
Body Mass Index
title Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameter
title_full Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameter
title_fullStr Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameter
title_full_unstemmed Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameter
title_short Renal Cell Carcinoma and Visceral Adipose Index: a new risk parameter
title_sort renal cell carcinoma and visceral adipose index a new risk parameter
topic Carcinoma
Renal Cell
Visceral Pain
Hypertension
Body Mass Index
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000500955&lng=en&tlng=en
work_keys_str_mv AT alperotunctemur renalcellcarcinomaandvisceraladiposeindexanewriskparameter
AT muratdursun renalcellcarcinomaandvisceraladiposeindexanewriskparameter
AT kutanozer renalcellcarcinomaandvisceraladiposeindexanewriskparameter
AT ozanhorsanali renalcellcarcinomaandvisceraladiposeindexanewriskparameter
AT eminozbek renalcellcarcinomaandvisceraladiposeindexanewriskparameter