C–C chemokine receptor 5 is essential for conventional NK cell trafficking and liver injury in a murine hepatitis virus-induced fulminant hepatic failure model

C–C chemokine receptor 5 is essential for conventional NK cell trafficking and liver injury in a murine hepatitis virus-induced fulminant hepatic failure model

Abstract Background Previous studies have demonstrated that natural killer (NK) cells migrated into the liver from peripheral organs and exerted cytotoxic effects on hepatocytes in virus-induced liver failure. Aim This study aimed to investigate the potential therapeutic role of chemokine receptors...

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Bibliographic Details
Main Authors: Yun-Hui Liu, Lin Zhu, Zhong-Wei Zhang, Ting-Ting Liu, Qiu-Yu Cheng, Meng Zhang, Yu-Xin Niu, Lin Ding, Wei-Ming Yan, Xiao-Ping Luo, Qin Ning, Tao Chen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Virus infection
Liver failure
NK cell
Chemotaxis
CCR5
Online Access:https://doi.org/10.1186/s12967-023-04665-8

Internet

https://doi.org/10.1186/s12967-023-04665-8

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