Fibroblast activation protein-α expression in fibroblasts is common in the tumor microenvironment of colorectal cancer and may serve as a therapeutic target

Fibroblast activation protein-α expression in fibroblasts is common in the tumor microenvironment of colorectal cancer and may serve as a therapeutic target

Background: Colorectal cancer (CRC) is still one of the leading causes of cancer death worldwide, emphasizing the need for further diagnostic and therapeutic approaches. Cancer invasion and metastasis are affected by the tumor microenvironment (TME), with cancer-associated fibroblasts (CAF) being th...

Full description

Bibliographic Details
Main Authors: K. Greimelmaier, N. Klopp, E. Mairinger, M. Wessolly, S. Borchert, J. Steinborn, K. W. Schmid, J. Wohlschlaeger, F. D. Mairinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Pathology and Oncology Research
Subjects:
colorectal cancer
tumor microenvironment
cancer-associated fibroblasts
fibroblast-activation protein
radioligand therapy
Online Access:https://www.por-journal.com/articles/10.3389/pore.2023.1611163/full

Internet

https://www.por-journal.com/articles/10.3389/pore.2023.1611163/full

Similar Items