Depression in Adolescents with Asperger’s Syndrome: Long-Term Outcome

Introduction Asperger Syndrome (AS) exhibits a particular set of difficulties, the foremost of them being the impairment in social interaction. Furthermore, adolescence by itself is a period burdened with many social challenges and distress. The attempt to adjust to them while having AS is much har...

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Main Authors: I. Nicolau, C. Voinea, L. Mateescu
Format: Article
Language:English
Published: Cambridge University Press 2022-06-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933822006976/type/journal_article
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author I. Nicolau
C. Voinea
L. Mateescu
author_facet I. Nicolau
C. Voinea
L. Mateescu
author_sort I. Nicolau
collection DOAJ
description Introduction Asperger Syndrome (AS) exhibits a particular set of difficulties, the foremost of them being the impairment in social interaction. Furthermore, adolescence by itself is a period burdened with many social challenges and distress. The attempt to adjust to them while having AS is much harder, thus it may constitute the premise for the onset of internalizing symptomatology, in particular depression. Objectives This study aimed to observe what factors either improved or hindered the long-term outcome. It was analyzed how the different types of interventions influenced the outcome of these individuals in terms of academic performance, social functioning, psychiatric relapses and quality of life. Methods Our lot was represented by 16 patients diagnosed with Asperger Syndrome and Major Depressive Disorder (MDD), followed up on a period between 1 to 10 years. The lot was divided into two groups, each with a different therapeutic plan. The main instruments used were clinical observation and parents’ assessments. Results In the first group, the adolescents, treated with a complex intervention which included also a psychotherapeutic component, were found to have a positive outcome, 71,42% of them having no other psychiatric comorbidity than Major Depressive Disorder. The adolescents in the second group, who were treated only with pharmacological treatment, were found to have a negative outcome. Conclusions The factors that were found to have the most important impact on the long-term outcome were: the integration in a psychotherapy programme, having family support, compliance with the pharmacological treatment and having MDD as the only psychiatric comorbidity. Disclosure No significant relationships.
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spelling doaj.art-989a0c3f46fb4b7a92b8b28355045e642023-11-17T05:07:19ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S272S27210.1192/j.eurpsy.2022.697Depression in Adolescents with Asperger’s Syndrome: Long-Term OutcomeI. Nicolau0C. Voinea1L. Mateescu2“Prof.Dr. Al. Obregia” Psychiatry Clinical Hospital, Child And Adolescent Psychiatry Department, Bucharest, Romania“Prof.Dr. Al. Obregia” Psychiatry Clinical Hospital, Child And Adolescent Psychiatry Department, Bucharest, Romania“Prof.Dr. Al. Obregia” Psychiatry Clinical Hospital, Child And Adolescent Psychiatry Department, Bucharest, Romania Carol Davila University of Medicine and Pharmacy, Child And Adolescent Psychiatry Department, Bucharest, Romania Introduction Asperger Syndrome (AS) exhibits a particular set of difficulties, the foremost of them being the impairment in social interaction. Furthermore, adolescence by itself is a period burdened with many social challenges and distress. The attempt to adjust to them while having AS is much harder, thus it may constitute the premise for the onset of internalizing symptomatology, in particular depression. Objectives This study aimed to observe what factors either improved or hindered the long-term outcome. It was analyzed how the different types of interventions influenced the outcome of these individuals in terms of academic performance, social functioning, psychiatric relapses and quality of life. Methods Our lot was represented by 16 patients diagnosed with Asperger Syndrome and Major Depressive Disorder (MDD), followed up on a period between 1 to 10 years. The lot was divided into two groups, each with a different therapeutic plan. The main instruments used were clinical observation and parents’ assessments. Results In the first group, the adolescents, treated with a complex intervention which included also a psychotherapeutic component, were found to have a positive outcome, 71,42% of them having no other psychiatric comorbidity than Major Depressive Disorder. The adolescents in the second group, who were treated only with pharmacological treatment, were found to have a negative outcome. Conclusions The factors that were found to have the most important impact on the long-term outcome were: the integration in a psychotherapy programme, having family support, compliance with the pharmacological treatment and having MDD as the only psychiatric comorbidity. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822006976/type/journal_articleadolescenceAspergerDepression
spellingShingle I. Nicolau
C. Voinea
L. Mateescu
Depression in Adolescents with Asperger’s Syndrome: Long-Term Outcome
European Psychiatry
adolescence
Asperger
Depression
title Depression in Adolescents with Asperger’s Syndrome: Long-Term Outcome
title_full Depression in Adolescents with Asperger’s Syndrome: Long-Term Outcome
title_fullStr Depression in Adolescents with Asperger’s Syndrome: Long-Term Outcome
title_full_unstemmed Depression in Adolescents with Asperger’s Syndrome: Long-Term Outcome
title_short Depression in Adolescents with Asperger’s Syndrome: Long-Term Outcome
title_sort depression in adolescents with asperger s syndrome long term outcome
topic adolescence
Asperger
Depression
url https://www.cambridge.org/core/product/identifier/S0924933822006976/type/journal_article
work_keys_str_mv AT inicolau depressioninadolescentswithaspergerssyndromelongtermoutcome
AT cvoinea depressioninadolescentswithaspergerssyndromelongtermoutcome
AT lmateescu depressioninadolescentswithaspergerssyndromelongtermoutcome