CUL4 E3 ligase regulates the proliferation and apoptosis of lung squamous cell carcinoma and small cell lung carcinoma

CUL4 E3 ligase regulates the proliferation and apoptosis of lung squamous cell carcinoma and small cell lung carcinoma

Objective: The E3 ligase, CRL4, plays diverse roles in different cellular processes, such as DNA damage, transcriptional regulation, cell cycle progression, and cell apoptosis. Our previous study showed that CUL4A and CUL4B had a strong association with tobacco smoking risk in lung squamous cell car...

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Bibliographic Details
Main Authors: Ting Li, Si Wu, Lei Jia, Wenfeng Cao, Yuan Yao, Gang Zhao, Hui Li
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-05-01
Series:Cancer Biology & Medicine
Subjects:
squamous cell lung cancer
small cell lung cancer
cul4a
cul4b
p21
foxo3a
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1615

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