Food supplements could be an effective improvement of diabetes mellitus: a review

Diabetes mellitus is a disease of endocrine and metabolism disorders, characterized by hyperglycemia, and increased risk of cardiovascular disease complications. Although oral hypoglycemic drugs have the effect of maintaining blood sugar control in diabetic patients, these drugs still have serious s...

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Main Authors: Xiangxi Meng, Qinyu Li, Ruyu Shi, Jiayin Chang, Hong Chang, Minhui Li
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2021-09-01
Series:Journal of Future Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772566921000069
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author Xiangxi Meng
Qinyu Li
Ruyu Shi
Jiayin Chang
Hong Chang
Minhui Li
author_facet Xiangxi Meng
Qinyu Li
Ruyu Shi
Jiayin Chang
Hong Chang
Minhui Li
author_sort Xiangxi Meng
collection DOAJ
description Diabetes mellitus is a disease of endocrine and metabolism disorders, characterized by hyperglycemia, and increased risk of cardiovascular disease complications. Although oral hypoglycemic drugs have the effect of maintaining blood sugar control in diabetic patients, these drugs still have serious side effects for many patients, such as gastrointestinal diseases related to acarbose. Recently, certain food supplements and their bioactive ingredients have been shown to improve diabetes mellitus and can be readily found in the marketplace. This literature review focuses on food supplements with a hypoglycemic function, with an emphasis on their biologically active ingredients and pharmacological effects. The biologically active ingredients can be divided into 6 categories: polyphenols, polysaccharides, terpenoids, saponins, alkaloids, and others. The sources, models used for their study, efficacy, and mechanisms of action of food supplements are described. The sources, models used for their study, efficacy, and mechanisms of action of food supplements are described, including regulation of microflora, modulation of glucose metabolism, and improvement in insulin function. By classifying medicinal plants that can be used as food supplements and their activities, we have provided useful information to support further investigation and application of food supplements to prevent or improve diabetes mellitus.
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spelling doaj.art-98a693f416904e0c8332aaf865d3e6f82022-12-22T04:42:00ZengKeAi Communications Co. Ltd.Journal of Future Foods2772-56692021-09-01116781Food supplements could be an effective improvement of diabetes mellitus: a reviewXiangxi Meng0Qinyu Li1Ruyu Shi2Jiayin Chang3Hong Chang4Minhui Li5Department of Pharmacy, Baotou Medical College, Baotou 014040, ChinaDepartment of Pharmacy, Baotou Medical College, Baotou 014040, ChinaDepartment of Pharmacy, Baotou Medical College, Baotou 014040, ChinaDepartment of Pharmacy, Baotou Medical College, Baotou 014040, ChinaDepartment of Pharmacy, Baotou Medical College, Baotou 014040, China; Corresponding author:Department of Pharmacy, Baotou Medical College, Baotou 014040, China; Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine, Hohhot 010020, China; Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot 010020, China; Inner Mongolia Key Laboratory of Characteristic Geoherbs Resources Protection and Utilization, Baotou Medical College, Baotou 014040, China; Inner Mongolia Engineering Research Center of the Planting and development of Astragalus Membranaceus of the Geoherbs, Baotou Medical College, Baotou 014040, China; Corresponding author:Diabetes mellitus is a disease of endocrine and metabolism disorders, characterized by hyperglycemia, and increased risk of cardiovascular disease complications. Although oral hypoglycemic drugs have the effect of maintaining blood sugar control in diabetic patients, these drugs still have serious side effects for many patients, such as gastrointestinal diseases related to acarbose. Recently, certain food supplements and their bioactive ingredients have been shown to improve diabetes mellitus and can be readily found in the marketplace. This literature review focuses on food supplements with a hypoglycemic function, with an emphasis on their biologically active ingredients and pharmacological effects. The biologically active ingredients can be divided into 6 categories: polyphenols, polysaccharides, terpenoids, saponins, alkaloids, and others. The sources, models used for their study, efficacy, and mechanisms of action of food supplements are described. The sources, models used for their study, efficacy, and mechanisms of action of food supplements are described, including regulation of microflora, modulation of glucose metabolism, and improvement in insulin function. By classifying medicinal plants that can be used as food supplements and their activities, we have provided useful information to support further investigation and application of food supplements to prevent or improve diabetes mellitus.http://www.sciencedirect.com/science/article/pii/S2772566921000069Food supplementBioactive ingredientDiabetes mellitus
spellingShingle Xiangxi Meng
Qinyu Li
Ruyu Shi
Jiayin Chang
Hong Chang
Minhui Li
Food supplements could be an effective improvement of diabetes mellitus: a review
Journal of Future Foods
Food supplement
Bioactive ingredient
Diabetes mellitus
title Food supplements could be an effective improvement of diabetes mellitus: a review
title_full Food supplements could be an effective improvement of diabetes mellitus: a review
title_fullStr Food supplements could be an effective improvement of diabetes mellitus: a review
title_full_unstemmed Food supplements could be an effective improvement of diabetes mellitus: a review
title_short Food supplements could be an effective improvement of diabetes mellitus: a review
title_sort food supplements could be an effective improvement of diabetes mellitus a review
topic Food supplement
Bioactive ingredient
Diabetes mellitus
url http://www.sciencedirect.com/science/article/pii/S2772566921000069
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