Prosthesis-patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prostheses
OBJECTIVE. Identification of predictors of dysfunction of biological aortic valve prostheses in the long-term period after surgical treatment.METHODS AND MATERIALS. We analyzed the completed treatment cases for the period from 2015 to 2020 and echocardiography data of 74 patients (42 men and 32 wome...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Pavlov First Saint Petersburg State Medical University
2022-09-01
|
| Series: | Вестник хирургии имени И.И. Грекова |
| Subjects: | |
| Online Access: | https://www.vestnik-grekova.ru/jour/article/view/1997 |
| _version_ | 1826962504636432384 |
|---|---|
| author | G. G. Khubulava Z. O. Maliev N. N. Shikhverdiev A. I. Lyubimov D. I. Ushakov |
| author_facet | G. G. Khubulava Z. O. Maliev N. N. Shikhverdiev A. I. Lyubimov D. I. Ushakov |
| author_sort | G. G. Khubulava |
| collection | DOAJ |
| description | OBJECTIVE. Identification of predictors of dysfunction of biological aortic valve prostheses in the long-term period after surgical treatment.METHODS AND MATERIALS. We analyzed the completed treatment cases for the period from 2015 to 2020 and echocardiography data of 74 patients (42 men and 32 women) with an average age of 67.0±4.2 years with bioprostheses implanted in the aortic position. The average follow-up period was 4 years. The transaortic flow velocity, the average and peak transvalvular gradients, the area of the effective opening of the prosthesis, the myocardium mass index, the thickness and mobility of the cusp of the biovalve were evaluated. The presence of the pronounced PPM in a patient was determined at iEOA values less than 0.65 cm2/m2, moderate - at values from 0.65 to 0.85 cm2/m2, mild - up to 0.85 cm2/m2.RESULTS. PPM was recorded in 27% of cases. Structural dysfunction was observed in 12.5% of cases, it mainly included stenosis of the bioprosthesis (10%). In 2.5% of cases, reintervention was performed for severe stenosis of the AV bioprosthesis. During the multifactorial analysis, we revealed that PPM was a predictor of the development of structural dysfunction of aortic valve bioprostheses in the long-term period after surgery (p<0.005). |
| first_indexed | 2024-04-10T02:19:39Z |
| format | Article |
| id | doaj.art-98ab19eda8054483b238dc4bb544561b |
| institution | Directory Open Access Journal |
| issn | 0042-4625 |
| language | Russian |
| last_indexed | 2025-02-18T02:15:51Z |
| publishDate | 2022-09-01 |
| publisher | Pavlov First Saint Petersburg State Medical University |
| record_format | Article |
| series | Вестник хирургии имени И.И. Грекова |
| spelling | doaj.art-98ab19eda8054483b238dc4bb544561b2024-11-26T10:43:56ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252022-09-011811212610.24884/0042-4625-2022-181-1-21-261383Prosthesis-patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prosthesesG. G. Khubulava0Z. O. Maliev1N. N. Shikhverdiev2A. I. Lyubimov3D. I. Ushakov4Military Medical AcademyMilitary Medical AcademyMilitary Medical AcademyMilitary Medical AcademyMilitary Medical AcademyOBJECTIVE. Identification of predictors of dysfunction of biological aortic valve prostheses in the long-term period after surgical treatment.METHODS AND MATERIALS. We analyzed the completed treatment cases for the period from 2015 to 2020 and echocardiography data of 74 patients (42 men and 32 women) with an average age of 67.0±4.2 years with bioprostheses implanted in the aortic position. The average follow-up period was 4 years. The transaortic flow velocity, the average and peak transvalvular gradients, the area of the effective opening of the prosthesis, the myocardium mass index, the thickness and mobility of the cusp of the biovalve were evaluated. The presence of the pronounced PPM in a patient was determined at iEOA values less than 0.65 cm2/m2, moderate - at values from 0.65 to 0.85 cm2/m2, mild - up to 0.85 cm2/m2.RESULTS. PPM was recorded in 27% of cases. Structural dysfunction was observed in 12.5% of cases, it mainly included stenosis of the bioprosthesis (10%). In 2.5% of cases, reintervention was performed for severe stenosis of the AV bioprosthesis. During the multifactorial analysis, we revealed that PPM was a predictor of the development of structural dysfunction of aortic valve bioprostheses in the long-term period after surgery (p<0.005).https://www.vestnik-grekova.ru/jour/article/view/1997prosthesis-patient mismatchaortic valvebioprosthesiscardiac surgerycalcification |
| spellingShingle | G. G. Khubulava Z. O. Maliev N. N. Shikhverdiev A. I. Lyubimov D. I. Ushakov Prosthesis-patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prostheses Вестник хирургии имени И.И. Грекова prosthesis-patient mismatch aortic valve bioprosthesis cardiac surgery calcification |
| title | Prosthesis-patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prostheses |
| title_full | Prosthesis-patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prostheses |
| title_fullStr | Prosthesis-patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prostheses |
| title_full_unstemmed | Prosthesis-patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prostheses |
| title_short | Prosthesis-patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prostheses |
| title_sort | prosthesis patient mismatch as a predictor of accelerated structural dysfunction of biological aortic valve prostheses |
| topic | prosthesis-patient mismatch aortic valve bioprosthesis cardiac surgery calcification |
| url | https://www.vestnik-grekova.ru/jour/article/view/1997 |
| work_keys_str_mv | AT ggkhubulava prosthesispatientmismatchasapredictorofacceleratedstructuraldysfunctionofbiologicalaorticvalveprostheses AT zomaliev prosthesispatientmismatchasapredictorofacceleratedstructuraldysfunctionofbiologicalaorticvalveprostheses AT nnshikhverdiev prosthesispatientmismatchasapredictorofacceleratedstructuraldysfunctionofbiologicalaorticvalveprostheses AT ailyubimov prosthesispatientmismatchasapredictorofacceleratedstructuraldysfunctionofbiologicalaorticvalveprostheses AT diushakov prosthesispatientmismatchasapredictorofacceleratedstructuraldysfunctionofbiologicalaorticvalveprostheses |