Microfluidic Capture of Mycobacterium tuberculosis from Clinical Samples for Culture-Free Whole-Genome Sequencing

Microfluidic Capture of Mycobacterium tuberculosis from Clinical Samples for Culture-Free Whole-Genome Sequencing

ABSTRACT Mycobacterium tuberculosis whole-genome sequencing (WGS) is a powerful tool as it can provide data on population diversity, drug resistance, disease transmission, and mixed infections. Successful WGS is still reliant on high concentrations of DNA obtained through M. tuberculosis culture. Mi...

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Bibliographic Details
Main Authors: Nabila Ismail, Anzaan Dippenaar, George Morgan, Melanie Grobbelaar, Felicia Wells, Jessica Caffry, Cristiana Morais, Krzysztof Gizynski, David McGurk, Eduardo Boada, Heather Murton, Robin M. Warren, Annelies Van Rie
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
Mycobacterium tuberculosis
tuberculosis
whole-genome sequencing
microfluidics
culture-free sequencing
cell capture
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01114-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01114-23

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