Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature
We present an unusual case of a 28-year-old female who had atypical trophoblastic proliferation on her endocervical curettage (ECC) performed at the time of a colposcopy. The indication for colposcopy was a Pap smear notable for atypical squamous cells of unknown significance, positive HPV. Initiall...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-06-01
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| Series: | Gynecologic Oncology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352578922000741 |
| _version_ | 1817981312763428864 |
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| author | Allison L. Brodsky Marianne Hom-Tedla Oluwole Fadare Michael T. McHale |
| author_facet | Allison L. Brodsky Marianne Hom-Tedla Oluwole Fadare Michael T. McHale |
| author_sort | Allison L. Brodsky |
| collection | DOAJ |
| description | We present an unusual case of a 28-year-old female who had atypical trophoblastic proliferation on her endocervical curettage (ECC) performed at the time of a colposcopy. The indication for colposcopy was a Pap smear notable for atypical squamous cells of unknown significance, positive HPV. Initially conservative management was pursued, but given persistent atypia the patient ultimately decided to proceed with definitive management via hysterectomy. Final histologic assessment demonstrated an epithelioid trophoblastic tumor (ETT). This case highlights the unusual scenario of ETT presenting as atypical trophoblastic cells on endocervical curettage and the possible evolution of an atypical placental site nodule into an ETT. |
| first_indexed | 2024-04-13T23:04:16Z |
| format | Article |
| id | doaj.art-98ae77bed89b4780a5af57163d106003 |
| institution | Directory Open Access Journal |
| issn | 2352-5789 |
| language | English |
| last_indexed | 2024-04-13T23:04:16Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Gynecologic Oncology Reports |
| spelling | doaj.art-98ae77bed89b4780a5af57163d1060032022-12-22T02:25:43ZengElsevierGynecologic Oncology Reports2352-57892022-06-0141100994Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literatureAllison L. Brodsky0Marianne Hom-Tedla1Oluwole Fadare2Michael T. McHale3University of California San Diego, Department of Gynecologic Oncology, San Diego, CA, USA; Corresponding author.at: 9280 Towne Center Drive, Unit 52, San Diego, CA 92121, 610-306-1544.University of California San Diego, Department of Gynecologic Oncology, San Diego, CA, USAUniversity of California San Diego, Department of Pathology, San Diego, CA, USAUniversity of California San Diego, Department of Gynecologic Oncology, San Diego, CA, USAWe present an unusual case of a 28-year-old female who had atypical trophoblastic proliferation on her endocervical curettage (ECC) performed at the time of a colposcopy. The indication for colposcopy was a Pap smear notable for atypical squamous cells of unknown significance, positive HPV. Initially conservative management was pursued, but given persistent atypia the patient ultimately decided to proceed with definitive management via hysterectomy. Final histologic assessment demonstrated an epithelioid trophoblastic tumor (ETT). This case highlights the unusual scenario of ETT presenting as atypical trophoblastic cells on endocervical curettage and the possible evolution of an atypical placental site nodule into an ETT.http://www.sciencedirect.com/science/article/pii/S2352578922000741Gestational trophoblastic neoplasiaEpithelial trophoblastic tumor |
| spellingShingle | Allison L. Brodsky Marianne Hom-Tedla Oluwole Fadare Michael T. McHale Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature Gynecologic Oncology Reports Gestational trophoblastic neoplasia Epithelial trophoblastic tumor |
| title | Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature |
| title_full | Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature |
| title_fullStr | Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature |
| title_full_unstemmed | Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature |
| title_short | Persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic Tumor: A case report and review of the literature |
| title_sort | persistent trophoblastic atypia on endocervical curettage found to be an epithelioid trophoblastic tumor a case report and review of the literature |
| topic | Gestational trophoblastic neoplasia Epithelial trophoblastic tumor |
| url | http://www.sciencedirect.com/science/article/pii/S2352578922000741 |
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