A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids
A patient with antisynthetase syndrome with pulmonary and muscular involvement was treated with immunosuppressive agents without corticosteroids. Rituximab was added to mycophenolate mofetil therapy with improvement in lung functional and imaging findings and normalization of creatine kinase levels.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2022-07-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/3324 |
| _version_ | 1828111918461616128 |
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| author | Agnieszka Ewa Sieradzka Bruno Naccini Massimiliano Fontana |
| author_facet | Agnieszka Ewa Sieradzka Bruno Naccini Massimiliano Fontana |
| author_sort | Agnieszka Ewa Sieradzka |
| collection | DOAJ |
| description | A patient with antisynthetase syndrome with pulmonary and muscular involvement was treated with immunosuppressive agents without corticosteroids. Rituximab was added to mycophenolate mofetil therapy with improvement in lung functional and imaging findings and normalization of creatine kinase levels. |
| first_indexed | 2024-04-11T11:43:33Z |
| format | Article |
| id | doaj.art-98ae8930a9d645aeb1f49631195e6c49 |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-04-11T11:43:33Z |
| publishDate | 2022-07-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-98ae8930a9d645aeb1f49631195e6c492022-12-22T04:25:46ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942022-07-0110.12890/2022_0033242859A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No CorticosteroidsAgnieszka Ewa Sieradzka0Bruno Naccini1Massimiliano Fontana2Private Practice, Riva San Vitale, Ticino, Switzerland Pneumology Service, Ospedale Beata Vergine, Mendrisio, Ticino, SwitzerlandAllergology and Clinical Immunology Service, Ospedale Beata Vergine, Mendrisio, Ticino, SwitzerlandA patient with antisynthetase syndrome with pulmonary and muscular involvement was treated with immunosuppressive agents without corticosteroids. Rituximab was added to mycophenolate mofetil therapy with improvement in lung functional and imaging findings and normalization of creatine kinase levels.https://www.ejcrim.com/index.php/EJCRIM/article/view/3324antisynthetase syndromeinterstitial lung diseasepolymyositis/dermatomyositisidiopathic inflammatory myopathy mycophenolate mofetilrituximabcorticosteroids. |
| spellingShingle | Agnieszka Ewa Sieradzka Bruno Naccini Massimiliano Fontana A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids European Journal of Case Reports in Internal Medicine antisynthetase syndrome interstitial lung disease polymyositis/dermatomyositis idiopathic inflammatory myopathy mycophenolate mofetil rituximab corticosteroids. |
| title | A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids |
| title_full | A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids |
| title_fullStr | A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids |
| title_full_unstemmed | A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids |
| title_short | A Case of Anti-Synthetase Syndrome Successfully Treated with Mycophenolate Mofetil and Rituximab but No Corticosteroids |
| title_sort | case of anti synthetase syndrome successfully treated with mycophenolate mofetil and rituximab but no corticosteroids |
| topic | antisynthetase syndrome interstitial lung disease polymyositis/dermatomyositis idiopathic inflammatory myopathy mycophenolate mofetil rituximab corticosteroids. |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/3324 |
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