Comparison of LC-MS and LC-DAD Methods of Detecting Abused Piperazine Designer Drugs

Comparison of LC-MS and LC-DAD Methods of Detecting Abused Piperazine Designer Drugs

Recreational use of piperazine designer drugs is a serious threat to human health. These compounds act on the body in a similar fashion to illegal drugs. They induce psychostimulatory effects as well as visual and auditory hallucinations to varying degrees. In many cases of poisoning and deaths, the...

Full description

Bibliographic Details
Main Authors:	Anna Welz, Marcin Koba, Piotr Kośliński, Joanna Siódmiak
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Series:	Journal of Clinical Medicine
Subjects:	piperazine designer drugs benzylpiperazine derivatives phenylpiperazine derivatives LC-MS LC-DAD drugs of abuse
Online Access:	https://www.mdpi.com/2077-0383/11/7/1758

Similar Items

Rapid Targeted Method of Detecting Abused Piperazine Designer Drugs
by: Anna Welz, et al.
Published: (2021-12-01)

Piperazine derivatives as dangerous abused compounds
by: Welz Anna, et al.
Published: (2020-12-01)

Development of a targeted GC/MS screening method and validation of an HPLC/DAD quantification method for piperazines–amphetamines mixtures in seized material
by: Yacine Boumrah, et al.
Published: (2014-09-01)

Pigments’ analysis of Citrus juicing making by‐products by LC‐MS/MS and LC‐DAD
by: Eleni D. Myrtsi, et al.
Published: (2022-01-01)

Development of an LC–DAD–MS-Based Method for the Analysis of Hydroxyanthracene Derivatives in Food Supplements and Plant Materials
by: Francesca Loschi, et al.
Published: (2022-03-01)

Simultaneous determination of 14 analgesics in postoperative analgesic solution by HPLC–DAD and LC–MS/MS
by: Manman Yao, et al.
Published: (2024-01-01)

Fast and Sensitive LC-DAD-ESI/MS Method for Analysis of Saikosaponins c, a, and d from the Roots of Bupleurum Falcatum (Sandaochaihu)
by: Jian Liang, et al.
Published: (2011-02-01)

LC/DAD determination of biogenic amines in serum of patients with diabetes mellitus, chronic urticaria or Hashimoto's thyroiditis
by: Trifunović-Macedoljan Jelena, et al.
Published: (2016-01-01)

Comparative Analysis of Amino Acid Profiles in Patients with Glioblastoma and Meningioma Using Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC-ESI-MS/MS)
by: Piotr Kośliński, et al.
Published: (2023-11-01)

Development of a New LC-MS/MS Screening Method for Detection of 120 NPS and 43 Drugs in Blood
by: Fabio Vaiano, et al.
Published: (2021-11-01)

Low Level of Allergens in the Argentinean Plant <i>Zuccagnia punctata Cav</i>.: Screening and Quality Control of North-Western Propolis Using an LC-DAD-QTOF System
by: Eliana Rita Solorzano, et al.
Published: (2019-08-01)

Comparison of the immunoassay method with the commercial and in-house LC-MS/MS methods for substance abuse in urine
by: Avcioglu Gamze, et al.
Published: (2023-10-01)

LC-MS/MS and LC-UV Determination of Moniliformin by Adding Lanthanide Ions to the Mobile Phase
by: Terenzio Bertuzzi, et al.
Published: (2019-09-01)

LC-MS/MS Application in Pharmacotoxicological Field: Current State and New Applications
by: Cristian D’Ovidio, et al.
Published: (2023-02-01)

Sustainable chromatographic quantitation of multi-antihypertensive medications: application on diverse combinations containing hydrochlorothiazide along with LC–MS/MS profiling of potential impurities: greenness and whiteness evaluation
by: Hoda M. Marzouk, et al.
Published: (2023-08-01)

Simultaneous determination of 9 CYP450 enzymes in human liver microsomes using LC-MS/MS
by: SHI Zhongbo, et al.
Published: (2021-02-01)

Synthesis and in silico study of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives as suitable therapeutic agents
by: Ghulam Hussain, et al.
Published: (2017-04-01)

A novel analytical method of 1-(3-trifluoromethylphenyl) piperazine and 1-(3-chlorophenyl) piperazine in fluids of drug addicts using liquid-liquid extraction-gas chromatographic/nitrogen-phosphorous detection
by: Jing Chang, et al.
Published: (2017-01-01)

Rapid and simple LC–MS/MS determination of urinary ethyl glucuronide, naltrexone, 6β-naltrexol, chlordiazepoxide, and norchlordiazepoxide for monitoring alcohol abuse
by: Yeong Eun Sim, et al.
Published: (2022-02-01)

Investigation on acquired palbociclib resistance by LC-MS based multi-omics analysis
by: Zhichao Xue, et al.
Published: (2023-01-01)

Simultaneous Determination of Carbamazepine and Carbamazepine-10,11-epoxide in Different Biological Matrices by LC-MS/MS
by: Andonie Dan, et al.
Published: (2017-09-01)

Synthesis and Antimicrobial Activity of New Mannich Bases with Piperazine Moiety
by: Sara Janowska, et al.
Published: (2023-07-01)

Development of the Validated Stability-Indicating Method for the Determination of Vortioxetine in Bulk and Pharmaceutical Formulation by HPLC-DAD, Stress Degradation Kinetics Studies and Detection of Degradation Products by LC-ESI-QTOF-MS
by: Karol Wróblewski, et al.
Published: (2022-03-01)

Chitin Determination in Residual Streams Derived From Insect Production by LC-ECD and LC-MS/MS Methods
by: Azkia Nurfikari, et al.
Published: (2021-12-01)

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)-Based Proteomics of Drug-Metabolizing Enzymes and Transporters
by: Jiapeng Li, et al.
Published: (2020-06-01)

LC–MS/MS separation and quantitation of ribavirin in chicken and comparison of different mass spectrometric platforms
by: Daokun Xu, et al.
Published: (2023-08-01)

Comparison of LC-MS<sup>3</sup> and LC-MRM Methods for Quantifying Amantadine and Its Application in Therapeutic Amantadine Monitoring in Human Plasma
by: Qiang Sun, et al.
Published: (2022-11-01)

Effects of Piperazine Derivative on Paclitaxel Pharmacokinetics
by: Jaeok Lee, et al.
Published: (2019-01-01)

A One-Pot Biginelli Synthesis and Characterization of Novel Dihydropyrimidinone Derivatives Containing Piperazine/Morpholine Moiety
by: Mashooq Ahmad Bhat, et al.
Published: (2018-06-01)

Stress degradation study of two oral antidiabetics, gliclazide and glipizide, and chemical analysis by LC and LC/MS methods
by: Gumieniczek Anna, et al.
Published: (2014-01-01)

Phenolic Characterization Using cLC-DAD Analysis and Evaluation of In Vitro and In Vivo Pharmacological Activities of <i>Ruta tuberculata</i> Forssk
by: Asma Saidi, et al.
Published: (2022-07-01)

LC-MS identification and preparative HPLC isolation of Frankenia pulverulenta phenolics with antioxidant and neuroprotective capacities in PC12 cell line
by: Rim Ben Mansour, et al.
Published: (2017-01-01)

Determination of 20 Kinds of Cephalosporins Residues in Animal Derived Food by QuEChERS-LC-MS/MS with Isotope Internal Standards Method
by: Xing XU, et al.
Published: (2022-12-01)

Simplified Procedure for General Synthesis of Monosubstituted Piperazines—From a Batch Reaction Vessel to a Flow (Microwave) Reactor
by: Dana Němečková, et al.
Published: (2020-05-01)

The Development of an Extraction Method for Simultaneously Analyzing Fatty Acids in Macroalgae Using SPE with Derivatization for LC–MS/MS
by: Taewoo Yum, et al.
Published: (2024-01-01)

An LcMYB111-LcHY5 Module Differentially Activates an <i>LcFLS</i> Promoter in Different Litchi Cultivars
by: Zhidan Xiao, et al.
Published: (2023-11-01)

Comparison of Different Techniques for the Determination of Platinized Cytostatic Drugs in Urine Samples
by: Marina Arenas, et al.
Published: (2022-11-01)

Simultaneous Determination of Cortisol, Cortisone, and Multiple Illicit Drugs in Hair among Female Drug Addicts with LC-MS/MS
by: Cailing Duan, et al.
Published: (2021-01-01)

Dried Plasma Spot Based LC–MS/MS Method for Monitoring of Meropenem in the Blood of Treated Patients
by: Haiwei Cao, et al.
Published: (2022-03-01)

Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C
by: Marius W. Baeken, et al.
Published: (2020-10-01)