A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern Nepal
<p><strong>Background:</strong> Carcinoma cervix is among a curable cancer, if identified at an early stage. Pap smear is a simple, safe, noninvasive, outdoor and effective method for detection of lesions of the cervix but it fails to localize the lesion. Cervical biopsy, on the ot...
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| Format: | Article |
| Language: | English |
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Association of Clinical Pathologists of Nepal
2018-09-01
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| Series: | Journal of Pathology of Nepal |
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| Online Access: | https://www.nepjol.info/index.php/JPN/article/view/20993 |
| _version_ | 1818874082601467904 |
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| author | Nirajan Mainali Neha Homagai Niraj Nepal Prabesh Choudhary |
| author_facet | Nirajan Mainali Neha Homagai Niraj Nepal Prabesh Choudhary |
| author_sort | Nirajan Mainali |
| collection | DOAJ |
| description | <p><strong>Background:</strong> Carcinoma cervix is among a curable cancer, if identified at an early stage. Pap smear is a simple, safe, noninvasive, outdoor and effective method for detection of lesions of the cervix but it fails to localize the lesion. Cervical biopsy, on the other hand is a gold standard but invasive technique.</p><p><strong>Materials and Methods:</strong> A prospective cross-sectional study was done in Nobel medical college from January 16, 2017 to January 15, 2018 where all pap smears received in a Department of Pathology were included in the study. However, only cases that had undergone both Pap smear and cervical biopsy were compared. Out of the 1492 pap smears, 118 cases underwent biopsy. Correlation was then done regarding cytological and histological diagnosis.</p><p><strong>Results: </strong>Majority of the cytological findings were normal. 7 patients of HSIL revealed moderate dysplasia and higher lesions in biopsy. 2 cases were that of adenocarcinoma which were diagnosed as inflammatory smear in Pap smear.<strong></strong></p><p><strong>Conclusion:</strong> Cervical Pap smear is reliable screening test to identify high grade squamous cell lesions and carcinoma, but it fails to localize the lesion and adenocarcinoma is hard to identify in a pap smear. Hence, cervical biopsy should be carried out to confirm the findings of Pap smear and in case of strong clinical suspicion.</p> |
| first_indexed | 2024-12-19T13:04:57Z |
| format | Article |
| id | doaj.art-98b015745ffa46678c9a036f3db8b85f |
| institution | Directory Open Access Journal |
| issn | 2091-0797 2091-0908 |
| language | English |
| last_indexed | 2024-12-19T13:04:57Z |
| publishDate | 2018-09-01 |
| publisher | Association of Clinical Pathologists of Nepal |
| record_format | Article |
| series | Journal of Pathology of Nepal |
| spelling | doaj.art-98b015745ffa46678c9a036f3db8b85f2022-12-21T20:20:06ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082018-09-01821389139210.3126/jpn.v8i2.2099316307A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern NepalNirajan MainaliNeha HomagaiNiraj NepalPrabesh Choudhary<p><strong>Background:</strong> Carcinoma cervix is among a curable cancer, if identified at an early stage. Pap smear is a simple, safe, noninvasive, outdoor and effective method for detection of lesions of the cervix but it fails to localize the lesion. Cervical biopsy, on the other hand is a gold standard but invasive technique.</p><p><strong>Materials and Methods:</strong> A prospective cross-sectional study was done in Nobel medical college from January 16, 2017 to January 15, 2018 where all pap smears received in a Department of Pathology were included in the study. However, only cases that had undergone both Pap smear and cervical biopsy were compared. Out of the 1492 pap smears, 118 cases underwent biopsy. Correlation was then done regarding cytological and histological diagnosis.</p><p><strong>Results: </strong>Majority of the cytological findings were normal. 7 patients of HSIL revealed moderate dysplasia and higher lesions in biopsy. 2 cases were that of adenocarcinoma which were diagnosed as inflammatory smear in Pap smear.<strong></strong></p><p><strong>Conclusion:</strong> Cervical Pap smear is reliable screening test to identify high grade squamous cell lesions and carcinoma, but it fails to localize the lesion and adenocarcinoma is hard to identify in a pap smear. Hence, cervical biopsy should be carried out to confirm the findings of Pap smear and in case of strong clinical suspicion.</p>https://www.nepjol.info/index.php/JPN/article/view/20993CarcinomaCervical biopsy, DysplasiaHigh gradeLow gradePap smears |
| spellingShingle | Nirajan Mainali Neha Homagai Niraj Nepal Prabesh Choudhary A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern Nepal Journal of Pathology of Nepal Carcinoma Cervical biopsy, Dysplasia High grade Low grade Pap smears |
| title | A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern Nepal |
| title_full | A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern Nepal |
| title_fullStr | A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern Nepal |
| title_full_unstemmed | A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern Nepal |
| title_short | A correlation study of cervical cytology on Pap smear with cervical biopsy in a tertiary hospital of Eastern Nepal |
| title_sort | correlation study of cervical cytology on pap smear with cervical biopsy in a tertiary hospital of eastern nepal |
| topic | Carcinoma Cervical biopsy, Dysplasia High grade Low grade Pap smears |
| url | https://www.nepjol.info/index.php/JPN/article/view/20993 |
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