Shift work and cardiovascular disease – pathways from circadian stress to morbidity

In order to establish a causal relation between shift work and cardiovascular disease (CVD), we need to verify the pathways from the former to the latter. This paper aims to review the current knowledge of the mechanisms between shift work and CVD. Shift work can increase the risk of CVD by several...

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Main Authors: Sampsa Puttonen, Mikko Härmä, Christer Hublin
Format: Article
Language:English
Published: Nordic Association of Occupational Safety and Health (NOROSH) 2010-03-01
Series:Scandinavian Journal of Work, Environment & Health
Subjects:
Online Access: https://www.sjweh.fi/show_abstract.php?abstract_id=2894
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author Sampsa Puttonen
Mikko Härmä
Christer Hublin
author_facet Sampsa Puttonen
Mikko Härmä
Christer Hublin
author_sort Sampsa Puttonen
collection DOAJ
description In order to establish a causal relation between shift work and cardiovascular disease (CVD), we need to verify the pathways from the former to the latter. This paper aims to review the current knowledge of the mechanisms between shift work and CVD. Shift work can increase the risk of CVD by several interrelated psychosocial, behavioral, and physiological mechanisms. The psychosocial mechanisms relate to difficulties in controlling working hours, decreased work–life balance, and poor recovery following work. The most probable behavioral changes are weight gain and smoking. The plausible physiological and biological mechanisms are related to the activation of the autonomic nervous system, inflammation, changed lipid and glucose metabolism, and related changes in the risk for atherosclerosis, metabolic syndrome, and type II diabetes. The data provide evidence for possible disease mechanisms between shift work and CVD, but compelling evidence on any specific mechanism is missing.
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spelling doaj.art-98b0a50cef4041e5835cdb0daa3e1f632022-12-21T18:35:44ZengNordic Association of Occupational Safety and Health (NOROSH)Scandinavian Journal of Work, Environment & Health0355-31401795-990X2010-03-013629610810.5271/sjweh.28942894Shift work and cardiovascular disease – pathways from circadian stress to morbiditySampsa Puttonen0Mikko HärmäChrister HublinCentre of Expertise on Human Factors at Work, Finnish Institute of Occupational Health, FI-00250 Helsinki, Finland.In order to establish a causal relation between shift work and cardiovascular disease (CVD), we need to verify the pathways from the former to the latter. This paper aims to review the current knowledge of the mechanisms between shift work and CVD. Shift work can increase the risk of CVD by several interrelated psychosocial, behavioral, and physiological mechanisms. The psychosocial mechanisms relate to difficulties in controlling working hours, decreased work–life balance, and poor recovery following work. The most probable behavioral changes are weight gain and smoking. The plausible physiological and biological mechanisms are related to the activation of the autonomic nervous system, inflammation, changed lipid and glucose metabolism, and related changes in the risk for atherosclerosis, metabolic syndrome, and type II diabetes. The data provide evidence for possible disease mechanisms between shift work and CVD, but compelling evidence on any specific mechanism is missing. https://www.sjweh.fi/show_abstract.php?abstract_id=2894 reviewstresscardiovascular diseasehealthcoronary heart diseaseshift workmorbidityworkhoursliterature reviewcvdcircadian stressworking hours
spellingShingle Sampsa Puttonen
Mikko Härmä
Christer Hublin
Shift work and cardiovascular disease – pathways from circadian stress to morbidity
Scandinavian Journal of Work, Environment & Health
review
stress
cardiovascular disease
health
coronary heart disease
shift work
morbidity
workhours
literature review
cvd
circadian stress
working hours
title Shift work and cardiovascular disease – pathways from circadian stress to morbidity
title_full Shift work and cardiovascular disease – pathways from circadian stress to morbidity
title_fullStr Shift work and cardiovascular disease – pathways from circadian stress to morbidity
title_full_unstemmed Shift work and cardiovascular disease – pathways from circadian stress to morbidity
title_short Shift work and cardiovascular disease – pathways from circadian stress to morbidity
title_sort shift work and cardiovascular disease pathways from circadian stress to morbidity
topic review
stress
cardiovascular disease
health
coronary heart disease
shift work
morbidity
workhours
literature review
cvd
circadian stress
working hours
url https://www.sjweh.fi/show_abstract.php?abstract_id=2894
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AT mikkoharma shiftworkandcardiovasculardiseasepathwaysfromcircadianstresstomorbidity
AT christerhublin shiftworkandcardiovasculardiseasepathwaysfromcircadianstresstomorbidity