Autophagy-Lysosomal Pathway as Potential Therapeutic Target in Parkinson’s Disease
Cellular quality control systems have gained much attention in recent decades. Among these, autophagy is a natural self-preservation mechanism that continuously eliminates toxic cellular components and acts as an anti-ageing process. It is vital for cell survival and to preserve homeostasis. Several...
Main Authors: | Srinivasa Reddy Bonam, Christine Tranchant, Sylviane Muller |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/12/3547 |
Similar Items
-
Protein Aggregation and Dysfunction of Autophagy-Lysosomal Pathway: A Vicious Cycle in Lysosomal Storage Diseases
by: Antonio Monaco, et al.
Published: (2020-03-01) -
The Emerging Role of the Lysosome in Parkinson’s Disease
by: Alba Navarro-Romero, et al.
Published: (2020-11-01) -
The Consequences of GBA Deficiency in the Autophagy–Lysosome System in Parkinson’s Disease Associated with GBA
by: Eddie Pradas, et al.
Published: (2023-01-01) -
Defective lysosomal acidification: a new prognostic marker and therapeutic target for neurodegenerative diseases
by: Chih Hung Lo, et al.
Published: (2023-06-01) -
Synergistic Effect of Mitochondrial and Lysosomal Dysfunction in Parkinson’s Disease
by: Flora Guerra, et al.
Published: (2019-05-01)