Isolated Breast Relapse after Metastatic Alveolar Rhabdomyosarcoma in a Young Premenarcheal Girl: What Could Have Been Done?

Alveolar rhabdomyosarcoma (RMS) is one of the most common pediatric soft-tissue neoplasms. Breast involvement either as primary tumor or metastasis is extremely rare. Herein, we report a case of primary limb alveolar RMS with breast metastases in a young premenarcheal girl that relapsed only to the...

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Main Authors: Raymond N. Haddad, Souad Ghattas, Paul-Henri Torbey
Format: Article
Language:English
Published: Karger Publishers 2019-11-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/504337
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author Raymond N. Haddad
Souad Ghattas
Paul-Henri Torbey
author_facet Raymond N. Haddad
Souad Ghattas
Paul-Henri Torbey
author_sort Raymond N. Haddad
collection DOAJ
description Alveolar rhabdomyosarcoma (RMS) is one of the most common pediatric soft-tissue neoplasms. Breast involvement either as primary tumor or metastasis is extremely rare. Herein, we report a case of primary limb alveolar RMS with breast metastases in a young premenarcheal girl that relapsed only to the metastatic breast site after achieving complete response. Accordingly, we believe that investigations of the mammary glands should be part of the routine diagnostic workup in adolescent females with RMS. Local therapeutic measures to control breast disease, including surgery or radiotherapy has to be considered for better prognosis. Newer radiation modalities aiming at reducing side effects should be developed.
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spelling doaj.art-98b2f0bd310a40608dc2a942b50641a52022-12-21T23:52:01ZengKarger PublishersCase Reports in Oncology1662-65752019-11-0112389089510.1159/000504337504337Isolated Breast Relapse after Metastatic Alveolar Rhabdomyosarcoma in a Young Premenarcheal Girl: What Could Have Been Done?Raymond N. HaddadSouad GhattasPaul-Henri TorbeyAlveolar rhabdomyosarcoma (RMS) is one of the most common pediatric soft-tissue neoplasms. Breast involvement either as primary tumor or metastasis is extremely rare. Herein, we report a case of primary limb alveolar RMS with breast metastases in a young premenarcheal girl that relapsed only to the metastatic breast site after achieving complete response. Accordingly, we believe that investigations of the mammary glands should be part of the routine diagnostic workup in adolescent females with RMS. Local therapeutic measures to control breast disease, including surgery or radiotherapy has to be considered for better prognosis. Newer radiation modalities aiming at reducing side effects should be developed.https://www.karger.com/Article/FullText/504337rare diseasealveolar rhabdomyosarcomabreast metastasispediatric tumor
spellingShingle Raymond N. Haddad
Souad Ghattas
Paul-Henri Torbey
Isolated Breast Relapse after Metastatic Alveolar Rhabdomyosarcoma in a Young Premenarcheal Girl: What Could Have Been Done?
Case Reports in Oncology
rare disease
alveolar rhabdomyosarcoma
breast metastasis
pediatric tumor
title Isolated Breast Relapse after Metastatic Alveolar Rhabdomyosarcoma in a Young Premenarcheal Girl: What Could Have Been Done?
title_full Isolated Breast Relapse after Metastatic Alveolar Rhabdomyosarcoma in a Young Premenarcheal Girl: What Could Have Been Done?
title_fullStr Isolated Breast Relapse after Metastatic Alveolar Rhabdomyosarcoma in a Young Premenarcheal Girl: What Could Have Been Done?
title_full_unstemmed Isolated Breast Relapse after Metastatic Alveolar Rhabdomyosarcoma in a Young Premenarcheal Girl: What Could Have Been Done?
title_short Isolated Breast Relapse after Metastatic Alveolar Rhabdomyosarcoma in a Young Premenarcheal Girl: What Could Have Been Done?
title_sort isolated breast relapse after metastatic alveolar rhabdomyosarcoma in a young premenarcheal girl what could have been done
topic rare disease
alveolar rhabdomyosarcoma
breast metastasis
pediatric tumor
url https://www.karger.com/Article/FullText/504337
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