Legionnaires’ Disease Outbreak in Murcia, Spain
An explosive outbreak of Legionnaires’ disease occurred in Murcia, Spain, in July 2001. More than 800 suspected cases were reported; 449 of these cases were confirmed, which made this the world’s largest outbreak of the disease reported to date. Dates of onset for confirmed cases ranged from June 26...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
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Centers for Disease Control and Prevention
2003-08-01
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Series: | Emerging Infectious Diseases |
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Online Access: | https://wwwnc.cdc.gov/eid/article/9/8/03-0337_article |
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author | Ana García-Fulgueiras Carmen Navarro Daniel Fenoll José García Paulino González-Diego Teresa Jiménez-Buñuales Miguel Rodriguez Rosa Lopez Francisco Pacheco Joaquín Ruiz Manuel Segovia Beatriz Baladrón Carmen Pelaz |
author_facet | Ana García-Fulgueiras Carmen Navarro Daniel Fenoll José García Paulino González-Diego Teresa Jiménez-Buñuales Miguel Rodriguez Rosa Lopez Francisco Pacheco Joaquín Ruiz Manuel Segovia Beatriz Baladrón Carmen Pelaz |
author_sort | Ana García-Fulgueiras |
collection | DOAJ |
description | An explosive outbreak of Legionnaires’ disease occurred in Murcia, Spain, in July 2001. More than 800 suspected cases were reported; 449 of these cases were confirmed, which made this the world’s largest outbreak of the disease reported to date. Dates of onset for confirmed cases ranged from June 26 to July 19 , with a case-fatality rate of 1%. The epidemic curve and geographic pattern from the 600 completed epidemiologic questionnaires indicated an outdoor point-source exposure in the northern part of the city. A case-control study matching 85 patients living outside the city of Murcia with two controls each was undertaken to identify the outbreak source; the epidemiologic investigation implicated the cooling towers at a city hospital. An environmental isolate from these towers with an identical molecular pattern as the clinical isolates was subsequently identified and supported that epidemiologic conclusion. |
first_indexed | 2024-04-13T10:57:58Z |
format | Article |
id | doaj.art-98b376329e064391866dba6963e2e826 |
institution | Directory Open Access Journal |
issn | 1080-6040 1080-6059 |
language | English |
last_indexed | 2024-04-13T10:57:58Z |
publishDate | 2003-08-01 |
publisher | Centers for Disease Control and Prevention |
record_format | Article |
series | Emerging Infectious Diseases |
spelling | doaj.art-98b376329e064391866dba6963e2e8262022-12-22T02:49:29ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592003-08-019891592110.3201/eid0908.030337Legionnaires’ Disease Outbreak in Murcia, SpainAna García-FulgueirasCarmen NavarroDaniel FenollJosé GarcíaPaulino González-DiegoTeresa Jiménez-BuñualesMiguel RodriguezRosa LopezFrancisco PachecoJoaquín RuizManuel SegoviaBeatriz BaladrónCarmen PelazAn explosive outbreak of Legionnaires’ disease occurred in Murcia, Spain, in July 2001. More than 800 suspected cases were reported; 449 of these cases were confirmed, which made this the world’s largest outbreak of the disease reported to date. Dates of onset for confirmed cases ranged from June 26 to July 19 , with a case-fatality rate of 1%. The epidemic curve and geographic pattern from the 600 completed epidemiologic questionnaires indicated an outdoor point-source exposure in the northern part of the city. A case-control study matching 85 patients living outside the city of Murcia with two controls each was undertaken to identify the outbreak source; the epidemiologic investigation implicated the cooling towers at a city hospital. An environmental isolate from these towers with an identical molecular pattern as the clinical isolates was subsequently identified and supported that epidemiologic conclusion.https://wwwnc.cdc.gov/eid/article/9/8/03-0337_articlecase-control studycommunity outbreakenvironmental exposureLegionnaires’ diseaseSpain |
spellingShingle | Ana García-Fulgueiras Carmen Navarro Daniel Fenoll José García Paulino González-Diego Teresa Jiménez-Buñuales Miguel Rodriguez Rosa Lopez Francisco Pacheco Joaquín Ruiz Manuel Segovia Beatriz Baladrón Carmen Pelaz Legionnaires’ Disease Outbreak in Murcia, Spain Emerging Infectious Diseases case-control study community outbreak environmental exposure Legionnaires’ disease Spain |
title | Legionnaires’ Disease Outbreak in Murcia, Spain |
title_full | Legionnaires’ Disease Outbreak in Murcia, Spain |
title_fullStr | Legionnaires’ Disease Outbreak in Murcia, Spain |
title_full_unstemmed | Legionnaires’ Disease Outbreak in Murcia, Spain |
title_short | Legionnaires’ Disease Outbreak in Murcia, Spain |
title_sort | legionnaires disease outbreak in murcia spain |
topic | case-control study community outbreak environmental exposure Legionnaires’ disease Spain |
url | https://wwwnc.cdc.gov/eid/article/9/8/03-0337_article |
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