Insecticide resistance in mosquitoes: Development, mechanisms and monitoring
Mosquito-borne diseases are of major public health concerns, mainly in tropical countries. Control of these diseases is primarily achieved through mosquito control. One of the major challenges encountered by mosquito control programmes is the development of resistance to insecticides by mosquitoes....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Faculty of Science, University of Peradeniya, Sri Lanka
2018-12-01
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| Series: | Ceylon Journal of Science |
| Subjects: | |
| Online Access: | https://cjs.sljol.info/articles/7547 |
| _version_ | 1828305242129694720 |
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| author | S. H. P. P. Karunaratne W. A. P. P. De Silva T. C. Weeraratne S. N. Surendran |
| author_facet | S. H. P. P. Karunaratne W. A. P. P. De Silva T. C. Weeraratne S. N. Surendran |
| author_sort | S. H. P. P. Karunaratne |
| collection | DOAJ |
| description | Mosquito-borne diseases are of major public health concerns, mainly in tropical countries. Control of these diseases is primarily achieved through mosquito control. One of the major challenges encountered by mosquito control programmes is the development of resistance to insecticides by mosquitoes. Increased detoxifying activity through over expression of insect metabolic enzymes and altered target sites with decreased sensitivity to insecticides are the two major mechanisms of resistance. This review article presents our knowledge on development of insecticide resistance and the underlying biochemical and molecular mechanisms of resistance to major classes of insecticides. Techniques available to monitor resistance and to understand the underlying mechanisms are also discussed. |
| first_indexed | 2024-04-13T14:26:31Z |
| format | Article |
| id | doaj.art-98b6351597994fe3b11ee16797c19340 |
| institution | Directory Open Access Journal |
| issn | 2513-2814 2513-230X |
| language | English |
| last_indexed | 2024-04-13T14:26:31Z |
| publishDate | 2018-12-01 |
| publisher | Faculty of Science, University of Peradeniya, Sri Lanka |
| record_format | Article |
| series | Ceylon Journal of Science |
| spelling | doaj.art-98b6351597994fe3b11ee16797c193402022-12-22T02:43:19ZengFaculty of Science, University of Peradeniya, Sri LankaCeylon Journal of Science2513-28142513-230X2018-12-0147429930910.4038/cjs.v47i4.75475725Insecticide resistance in mosquitoes: Development, mechanisms and monitoringS. H. P. P. Karunaratne0W. A. P. P. De Silva1T. C. Weeraratne2S. N. Surendran3University of PeradeniyaUniversity of PeradeniyaUniversity of PeradeniyaUniversity of JaffnaMosquito-borne diseases are of major public health concerns, mainly in tropical countries. Control of these diseases is primarily achieved through mosquito control. One of the major challenges encountered by mosquito control programmes is the development of resistance to insecticides by mosquitoes. Increased detoxifying activity through over expression of insect metabolic enzymes and altered target sites with decreased sensitivity to insecticides are the two major mechanisms of resistance. This review article presents our knowledge on development of insecticide resistance and the underlying biochemical and molecular mechanisms of resistance to major classes of insecticides. Techniques available to monitor resistance and to understand the underlying mechanisms are also discussed.https://cjs.sljol.info/articles/7547mosquito controlinsecticide resistanceresistance mechanismsmetabolic resistancetarget-site insensitivitymonitoring insecticide resistance |
| spellingShingle | S. H. P. P. Karunaratne W. A. P. P. De Silva T. C. Weeraratne S. N. Surendran Insecticide resistance in mosquitoes: Development, mechanisms and monitoring Ceylon Journal of Science mosquito control insecticide resistance resistance mechanisms metabolic resistance target-site insensitivity monitoring insecticide resistance |
| title | Insecticide resistance in mosquitoes: Development, mechanisms and monitoring |
| title_full | Insecticide resistance in mosquitoes: Development, mechanisms and monitoring |
| title_fullStr | Insecticide resistance in mosquitoes: Development, mechanisms and monitoring |
| title_full_unstemmed | Insecticide resistance in mosquitoes: Development, mechanisms and monitoring |
| title_short | Insecticide resistance in mosquitoes: Development, mechanisms and monitoring |
| title_sort | insecticide resistance in mosquitoes development mechanisms and monitoring |
| topic | mosquito control insecticide resistance resistance mechanisms metabolic resistance target-site insensitivity monitoring insecticide resistance |
| url | https://cjs.sljol.info/articles/7547 |
| work_keys_str_mv | AT shppkarunaratne insecticideresistanceinmosquitoesdevelopmentmechanismsandmonitoring AT wappdesilva insecticideresistanceinmosquitoesdevelopmentmechanismsandmonitoring AT tcweeraratne insecticideresistanceinmosquitoesdevelopmentmechanismsandmonitoring AT snsurendran insecticideresistanceinmosquitoesdevelopmentmechanismsandmonitoring |