Rapid generation of purified human RPE from pluripotent stem cells using 2D cultures and lipoprotein uptake-based sorting

Rapid generation of purified human RPE from pluripotent stem cells using 2D cultures and lipoprotein uptake-based sorting

Abstract Background Despite increasing demand, current protocols for human pluripotent stem cell (hPSC)-derived retinal pigment epithelium (RPE) remain time, labor, and cost intensive. Additionally, absence of robust methods for selective RPE purification and removal of non-RPE cell impurities preve...

Full description

Bibliographic Details
Main Authors: Fabio Michelet, Aishwarya Balasankar, Nickolas Teo, Lawrence W. Stanton, Shweta Singhal
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Stem Cell Research & Therapy
Online Access:https://doi.org/10.1186/s13287-020-1568-3

Similar Items

Similar Items