Orlistat Mitigates Oxidative Stress-Linked Myocardial Damage via NF-κβ- and Caspase-Dependent Activities in Obese Rats

Orlistat Mitigates Oxidative Stress-Linked Myocardial Damage via NF-κβ- and Caspase-Dependent Activities in Obese Rats

Oxidative stress contributes to major complications of obesity. This study intended to identify whether orlistat could mitigate myocardial damage in obese animal models. The tested rats were divided into two groups and fed either with normal chow (<i>n</i> = 6 per group) or with a high-f...

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Bibliographic Details
Main Authors: Zaidatul Akmal Othman, Zaida Zakaria, Joseph Bagi Suleiman, Khairul Mohd Fadzli Mustaffa, Nur Asyilla Che Jalil, Wan Syaheedah Wan Ghazali, Ninie Nadia Zulkipli, Mahaneem Mohamed
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
orlistat
obesity
oxidative stress
inflammation
apoptosis
Online Access:https://www.mdpi.com/1422-0067/23/18/10266

Internet

https://www.mdpi.com/1422-0067/23/18/10266

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