Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problem
ABSTRACT Objective: Home nebulizers are routinely used in the treatment of patients with cystic fibrosis (CF). This study aims to evaluate the contamination of nebulizers used for CF patients, that are chronically colonized by Pseudomonas aeruginosa, and the association of nebulizer contamination w...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Pneumologia e Tisiologia
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| Series: | Jornal Brasileiro de Pneumologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000300203&lng=en&tlng=en |
| _version_ | 1811310004684193792 |
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| author | Barbara Riquena Luciana de Freitas Velloso Monte Agnaldo José Lopes Luiz Vicente Ribeiro Ferreira da Silva-Filho Neiva Damaceno Evanirso da Silva Aquino Paulo Jose Cauduro Marostica José Dirceu Ribeiro |
| author_facet | Barbara Riquena Luciana de Freitas Velloso Monte Agnaldo José Lopes Luiz Vicente Ribeiro Ferreira da Silva-Filho Neiva Damaceno Evanirso da Silva Aquino Paulo Jose Cauduro Marostica José Dirceu Ribeiro |
| author_sort | Barbara Riquena |
| collection | DOAJ |
| description | ABSTRACT Objective: Home nebulizers are routinely used in the treatment of patients with cystic fibrosis (CF). This study aims to evaluate the contamination of nebulizers used for CF patients, that are chronically colonized by Pseudomonas aeruginosa, and the association of nebulizer contamination with cleaning, decontamination and drying practices. Methods: A cross-sectional, observational, multicenter study was conducted in seven CF reference centers in Brazil to obtain data from medical records, structured interviews with patients/caregivers were performed, and nebulizer’s parts (interface and cup) were collected for microbiological culture. Results: overall, 77 CF patients were included. The frequency of nebulizer contamination was 71.6%. Candida spp. (52.9%), Stenotrophomonas maltophilia (11.9%), non-mucoid P. aeruginosa (4.8%), Staphylococcus aureus (4.8%) and Burkholderia cepacia complex (2.4%) were the most common isolated pathogens. The frequency of nebulizers’ hygiene was 97.4%, and 70.3% of patients reported cleaning, disinfection and drying the nebulizers. The use of tap water in cleaning method and outdoor drying of the parts significantly increased (9.10 times) the chance of nebulizers’ contamination. Conclusion: Despite the high frequency hygiene of the nebulizers reported, the cleaning and disinfection methods used were often inadequate. A significant proportion of nebulizers was contaminated with potentially pathogenic microorganisms for CF patients. These findings support the need to include patients/caregivers in educational programs and / or new strategies for delivering inhaled antibiotics. |
| first_indexed | 2024-04-13T09:52:07Z |
| format | Article |
| id | doaj.art-98b9d1f79ab540d4b391eacd46335eaa |
| institution | Directory Open Access Journal |
| issn | 1806-3756 |
| language | English |
| last_indexed | 2024-04-13T09:52:07Z |
| publisher | Sociedade Brasileira de Pneumologia e Tisiologia |
| record_format | Article |
| series | Jornal Brasileiro de Pneumologia |
| spelling | doaj.art-98b9d1f79ab540d4b391eacd46335eaa2022-12-22T02:51:34ZengSociedade Brasileira de Pneumologia e TisiologiaJornal Brasileiro de Pneumologia1806-375645310.1590/1806-3713/e20170351S1806-37132019000300203Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problemBarbara RiquenaLuciana de Freitas Velloso MonteAgnaldo José LopesLuiz Vicente Ribeiro Ferreira da Silva-FilhoNeiva DamacenoEvanirso da Silva AquinoPaulo Jose Cauduro MarosticaJosé Dirceu RibeiroABSTRACT Objective: Home nebulizers are routinely used in the treatment of patients with cystic fibrosis (CF). This study aims to evaluate the contamination of nebulizers used for CF patients, that are chronically colonized by Pseudomonas aeruginosa, and the association of nebulizer contamination with cleaning, decontamination and drying practices. Methods: A cross-sectional, observational, multicenter study was conducted in seven CF reference centers in Brazil to obtain data from medical records, structured interviews with patients/caregivers were performed, and nebulizer’s parts (interface and cup) were collected for microbiological culture. Results: overall, 77 CF patients were included. The frequency of nebulizer contamination was 71.6%. Candida spp. (52.9%), Stenotrophomonas maltophilia (11.9%), non-mucoid P. aeruginosa (4.8%), Staphylococcus aureus (4.8%) and Burkholderia cepacia complex (2.4%) were the most common isolated pathogens. The frequency of nebulizers’ hygiene was 97.4%, and 70.3% of patients reported cleaning, disinfection and drying the nebulizers. The use of tap water in cleaning method and outdoor drying of the parts significantly increased (9.10 times) the chance of nebulizers’ contamination. Conclusion: Despite the high frequency hygiene of the nebulizers reported, the cleaning and disinfection methods used were often inadequate. A significant proportion of nebulizers was contaminated with potentially pathogenic microorganisms for CF patients. These findings support the need to include patients/caregivers in educational programs and / or new strategies for delivering inhaled antibiotics.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000300203&lng=en&tlng=enFibrose císticaPseudomonas aeruginosaNebulizadores e vaporizadoresContaminação de equipamentoEsterilização |
| spellingShingle | Barbara Riquena Luciana de Freitas Velloso Monte Agnaldo José Lopes Luiz Vicente Ribeiro Ferreira da Silva-Filho Neiva Damaceno Evanirso da Silva Aquino Paulo Jose Cauduro Marostica José Dirceu Ribeiro Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problem Jornal Brasileiro de Pneumologia Fibrose cística Pseudomonas aeruginosa Nebulizadores e vaporizadores Contaminação de equipamento Esterilização |
| title | Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problem |
| title_full | Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problem |
| title_fullStr | Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problem |
| title_full_unstemmed | Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problem |
| title_short | Microbiological contamination of nebulizers used by cystic fibrosis patients: an underestimated problem |
| title_sort | microbiological contamination of nebulizers used by cystic fibrosis patients an underestimated problem |
| topic | Fibrose cística Pseudomonas aeruginosa Nebulizadores e vaporizadores Contaminação de equipamento Esterilização |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000300203&lng=en&tlng=en |
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