T cell aging and Alzheimer’s disease
The brain has long been considered an immune-privileged organ due to the presence of the blood-brain barrier (BBB). However, recent discoveries have revealed the underestimated role of T cells in the brain through the meningeal lymphatic system. Age is the primary risk factor for Alzheimer’s disease...
Main Authors: | Lin Guo, Xiaoting Li, Timothy Gould, Zhan-You Wang, Wenqiang Cao |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-04-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1154699/full |
Similar Items
-
Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the “obesity paradox”
by: Logan V. Vick, et al.
Published: (2023-01-01) -
MicroRNA Functions in Thymic Biology: Thymic Development and Involution
by: Minwen Xu, et al.
Published: (2018-09-01) -
Thymic Engraftment by in vitro-Derived Progenitor T Cells in Young and Aged Mice
by: Jastaranpreet Singh, et al.
Published: (2020-08-01) -
The effect of age on thymic function
by: Donald B. Palmer
Published: (2013-10-01) -
Klf4 protects thymus integrity during late pregnancy
by: Lucyle Depoërs, et al.
Published: (2023-04-01)