GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism

GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism

Summary: Prostate cancer (PCa) is a serious health concern for men due to its high incidence and mortality rate. The first therapy typically adopted is androgen deprivation therapy (ADT). However, patient response to ADT varies, and 20–30% of PCa cases develop into castration-resistant prostate canc...

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Bibliographic Details
Main Authors: Rui Wang, Qi Min, Yongjian Guo, Yuxin Zhou, Xin Zhang, Dechao Wang, Yuan Gao, Libin Wei
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Classification Description
Molecular biology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422400467X

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http://www.sciencedirect.com/science/article/pii/S258900422400467X

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