Assessing acceptability of the fourth dose against COVID-19 among Chinese adults: A population-based survey

Coronavirus disease 2019 (COVID-19) has wreaked havoc across the globe for approximately three years. Vaccination is a key factor to ending this pandemic, but its protective effect diminishes over time. A second booster dose at the right time is needed. To explore the willingness to receive the four...

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Main Authors: Chenyuan Qin, Min Du, Yaping Wang, Qiao Liu, Wenxin Yan, Liyuan Tao, Min Liu, Jue Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2023-01-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2023.2186108
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author Chenyuan Qin
Min Du
Yaping Wang
Qiao Liu
Wenxin Yan
Liyuan Tao
Min Liu
Jue Liu
author_facet Chenyuan Qin
Min Du
Yaping Wang
Qiao Liu
Wenxin Yan
Liyuan Tao
Min Liu
Jue Liu
author_sort Chenyuan Qin
collection DOAJ
description Coronavirus disease 2019 (COVID-19) has wreaked havoc across the globe for approximately three years. Vaccination is a key factor to ending this pandemic, but its protective effect diminishes over time. A second booster dose at the right time is needed. To explore the willingness to receive the fourth dose of the COVID-19 vaccine and its influencing factors, we commenced a national, cross-sectional and anonymous survey in mainland China among people aged 18 and above from October 24 to November 7, 2022. A total of 3,224 respondents were eventually included. The acceptance rate of the fourth dose was 81.1% (95% CI: 79.8–82.5%), while it was 72.6% (95% CI: 71.1–74.2%) for a heterologous booster. Confidence in current domestic situation and the effectiveness of previous vaccinations, and uncertainty about extra protection were the main reasons for vaccine hesitancy. Perceived benefit (aOR = 1.29, 95% CI: 1.159–1.40) and cues to action (aOR = 1.73, 95% CI: 1.60–1.88) were positively associated with the vaccine acceptance, whereas perceived barriers (aOR = 0.78, 95% CI: 0.72–0.84) and self-efficacy (aOR = 0.79, 95% CI: 0.71–0.89) were both negatively associated with it. Additionally, sex, age, COVID-19 vaccination history, time for social media, and satisfaction with the government’s response to COVID-19 were also factors affecting vaccination intention. Factors influencing the intention of heterologous booster were similar to the above results. It is of profound theoretical and practical significance to clarify the population’s willingness to vaccinate in advance and explore the relevant influencing factors for the subsequent development and promotion of the fourth-dose vaccination strategies.
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spelling doaj.art-98ce91bb2fb74f6aad721c3ee8e124a42023-09-26T13:25:48ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-01-0119110.1080/21645515.2023.21861082186108Assessing acceptability of the fourth dose against COVID-19 among Chinese adults: A population-based surveyChenyuan Qin0Min Du1Yaping Wang2Qiao Liu3Wenxin Yan4Liyuan Tao5Min Liu6Jue Liu7Peking UniversityPeking UniversityPeking UniversityPeking UniversityPeking UniversityPeking University Third HospitalPeking UniversityPeking UniversityCoronavirus disease 2019 (COVID-19) has wreaked havoc across the globe for approximately three years. Vaccination is a key factor to ending this pandemic, but its protective effect diminishes over time. A second booster dose at the right time is needed. To explore the willingness to receive the fourth dose of the COVID-19 vaccine and its influencing factors, we commenced a national, cross-sectional and anonymous survey in mainland China among people aged 18 and above from October 24 to November 7, 2022. A total of 3,224 respondents were eventually included. The acceptance rate of the fourth dose was 81.1% (95% CI: 79.8–82.5%), while it was 72.6% (95% CI: 71.1–74.2%) for a heterologous booster. Confidence in current domestic situation and the effectiveness of previous vaccinations, and uncertainty about extra protection were the main reasons for vaccine hesitancy. Perceived benefit (aOR = 1.29, 95% CI: 1.159–1.40) and cues to action (aOR = 1.73, 95% CI: 1.60–1.88) were positively associated with the vaccine acceptance, whereas perceived barriers (aOR = 0.78, 95% CI: 0.72–0.84) and self-efficacy (aOR = 0.79, 95% CI: 0.71–0.89) were both negatively associated with it. Additionally, sex, age, COVID-19 vaccination history, time for social media, and satisfaction with the government’s response to COVID-19 were also factors affecting vaccination intention. Factors influencing the intention of heterologous booster were similar to the above results. It is of profound theoretical and practical significance to clarify the population’s willingness to vaccinate in advance and explore the relevant influencing factors for the subsequent development and promotion of the fourth-dose vaccination strategies.http://dx.doi.org/10.1080/21645515.2023.2186108health belief modelcovid-19vaccine acceptancefourth dosevaccination
spellingShingle Chenyuan Qin
Min Du
Yaping Wang
Qiao Liu
Wenxin Yan
Liyuan Tao
Min Liu
Jue Liu
Assessing acceptability of the fourth dose against COVID-19 among Chinese adults: A population-based survey
Human Vaccines & Immunotherapeutics
health belief model
covid-19
vaccine acceptance
fourth dose
vaccination
title Assessing acceptability of the fourth dose against COVID-19 among Chinese adults: A population-based survey
title_full Assessing acceptability of the fourth dose against COVID-19 among Chinese adults: A population-based survey
title_fullStr Assessing acceptability of the fourth dose against COVID-19 among Chinese adults: A population-based survey
title_full_unstemmed Assessing acceptability of the fourth dose against COVID-19 among Chinese adults: A population-based survey
title_short Assessing acceptability of the fourth dose against COVID-19 among Chinese adults: A population-based survey
title_sort assessing acceptability of the fourth dose against covid 19 among chinese adults a population based survey
topic health belief model
covid-19
vaccine acceptance
fourth dose
vaccination
url http://dx.doi.org/10.1080/21645515.2023.2186108
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