Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols
The fraction of sterols and triterpenic dialcohols from unsaponifiable of virgin olive oil has been tested for Its possible antiinflamatory activity. The topical administration of these products produced a potent antioedematous effect, in the auricular oedema induced by TPA (12-0-tetradecanoylphorbo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Consejo Superior de Investigaciones Científicas
1997-04-01
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| Series: | Grasas y Aceites |
| Subjects: | |
| Online Access: | http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/775 |
| _version_ | 1818737711266136064 |
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| author | R. de la Puerta R. Maestro Durán V. Ruiz Gutiérrez |
| author_facet | R. de la Puerta R. Maestro Durán V. Ruiz Gutiérrez |
| author_sort | R. de la Puerta |
| collection | DOAJ |
| description | The fraction of sterols and triterpenic dialcohols from unsaponifiable of virgin olive oil has been tested for Its possible antiinflamatory activity. The topical administration of these products produced a potent antioedematous effect, in the auricular oedema induced by TPA (12-0-tetradecanoylphorbol acetate) in experimental animals. This test has been widely used to determine the antiinflamatory action of phospholipase A2 inhibitors. The measure of myeloperoxidase, marker enzyme of the accumulation of neutrophils in the inflamed tissue, demonstrated a significant reduction of the cellular infiltration produced by assayed fraction. |
| first_indexed | 2024-12-18T00:57:23Z |
| format | Article |
| id | doaj.art-98cf425d813844adbb83269ed1fd9cfe |
| institution | Directory Open Access Journal |
| issn | 0017-3495 1988-4214 |
| language | English |
| last_indexed | 2024-12-18T00:57:23Z |
| publishDate | 1997-04-01 |
| publisher | Consejo Superior de Investigaciones Científicas |
| record_format | Article |
| series | Grasas y Aceites |
| spelling | doaj.art-98cf425d813844adbb83269ed1fd9cfe2022-12-21T21:26:28ZengConsejo Superior de Investigaciones CientíficasGrasas y Aceites0017-34951988-42141997-04-01482939510.3989/gya.1997.v48.i2.775765Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcoholsR. de la Puerta0R. Maestro Durán1V. Ruiz Gutiérrez2Dpto. Farmacia, Tecnología Farmacéutica y Farmacología, Facultad de Farmacia, SevillaInstituto de la Grasa (C.S.I.C.).Instituto de la Grasa (C.S.I.C.).The fraction of sterols and triterpenic dialcohols from unsaponifiable of virgin olive oil has been tested for Its possible antiinflamatory activity. The topical administration of these products produced a potent antioedematous effect, in the auricular oedema induced by TPA (12-0-tetradecanoylphorbol acetate) in experimental animals. This test has been widely used to determine the antiinflamatory action of phospholipase A2 inhibitors. The measure of myeloperoxidase, marker enzyme of the accumulation of neutrophils in the inflamed tissue, demonstrated a significant reduction of the cellular infiltration produced by assayed fraction.http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/775antiinflamatory activitysteroltriterpene alcoholvirgin olive oil. |
| spellingShingle | R. de la Puerta R. Maestro Durán V. Ruiz Gutiérrez Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols Grasas y Aceites antiinflamatory activity sterol triterpene alcohol virgin olive oil. |
| title | Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols |
| title_full | Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols |
| title_fullStr | Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols |
| title_full_unstemmed | Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols |
| title_short | Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols |
| title_sort | pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols |
| topic | antiinflamatory activity sterol triterpene alcohol virgin olive oil. |
| url | http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/775 |
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