Association Between Shock Index and Post-Emergency Intubation Hypotension in Patients Who Called the Rapid Response Team at Dr. Cipto Mangunkusumo Hospital

Introduction: Hypotension is an acute complication following Emergency Endotracheal Intubation (ETI) in populations who called the Rapid Response Team (RRT). Thus, a fast and simple tool is needed to identify the risk of Post-emergency Intubation Hypotension (PIH). Shock Index (SI) pre-intubation is...

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Main Authors: Herlina Rahmah, Asri Adisasmita, Sidharta Kusuma Manggala, Adhrie Sugiarto, Fadiah Zahrina, Prita Rosdiana
Format: Article
Language:English
Published: Universitas Airlangga, Faculty of Medicine 2023-01-01
Series:Indonesian Journal of Anesthesiology and Reanimation (IJAR)
Subjects:
Online Access:https://e-journal.unair.ac.id/IJAR/article/view/41003
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author Herlina Rahmah
Asri Adisasmita
Sidharta Kusuma Manggala
Adhrie Sugiarto
Fadiah Zahrina
Prita Rosdiana
author_facet Herlina Rahmah
Asri Adisasmita
Sidharta Kusuma Manggala
Adhrie Sugiarto
Fadiah Zahrina
Prita Rosdiana
author_sort Herlina Rahmah
collection DOAJ
description Introduction: Hypotension is an acute complication following Emergency Endotracheal Intubation (ETI) in populations who called the Rapid Response Team (RRT). Thus, a fast and simple tool is needed to identify the risk of Post-emergency Intubation Hypotension (PIH). Shock Index (SI) pre-intubation is one of the potential factors to predict PIH. Objective: To measure the association between shock index with post-emergency intubation hypotension after calling for the RRT. Materials and Methods: This research is a cohort retrospective study that analyzed 171 patients aged ≥18 years who have called RRT and underwent an emergency ETI. The cut-off point for SI was determined using the ROC curve to predict PIH. The modification effect was evaluated using stratification analysis. Data were analyzed using cox regression to determine the likelihood of SI in the cause of hypotension. Result: A total of 92 patients (53.8%) underwent post-emergency intubation hypotension. The SI cut-off point of 0.9 had a sensitivity of 82.6% and a specificity of 67.1% for predicting PIH (Area Under Curve (AUC) 0.81; 95% CI 0.754–0.882, p <0.05). The increased risk of PIH associated with high SI score was an aRR of 1.9; 95% CI 1.03–3.57, a p-value of 0.040 among those with sepsis, and an aRR of 7.9, 95% CI 2.36–26.38, a p-value of 0.001 among those without sepsis. Conclusion: This study showed that a high SI score was associated with PIH after being controlled with other PIH risk variables. The risk of PIH associated with SI score modestly increased (2-fold increase) in those with sepsis and significantly increased (8-fold increase) in those without sepsis.
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spelling doaj.art-98cfd212808643cd90abf571ea88892c2023-08-02T02:02:50ZengUniversitas Airlangga, Faculty of MedicineIndonesian Journal of Anesthesiology and Reanimation (IJAR)2722-45542686-021X2023-01-0151273610.20473/ijar.V5I12023.27-3639074Association Between Shock Index and Post-Emergency Intubation Hypotension in Patients Who Called the Rapid Response Team at Dr. Cipto Mangunkusumo HospitalHerlina Rahmah0https://orcid.org/0000-0002-5689-3595Asri Adisasmita1https://orcid.org/0000-0002-8859-7862Sidharta Kusuma Manggala2https://orcid.org/0000-0002-0974-5864Adhrie Sugiarto3https://orcid.org/0000-0003-2542-1373Fadiah Zahrina4https://orcid.org/0000-0002-8026-3075Prita Rosdiana5https://orcid.org/0000-0002-7664-6751Epidemiology, Faculty of Public Health Universitas IndonesiaDepartment of Epidemiology, Faculty of Public Health Universitas Indonesia, Depok 16424, IndonesiaTim Medis Reaksi Cepat, Dr. Cipto Mangunkusumo National General Hospital, IndonesiaTim Medis Reaksi Cepat, Dr. Cipto Mangunkusumo National General Hospital, IndonesiaTim Medis Reaksi Cepat, Dr. Cipto Mangunkusumo National General Hospital, IndonesiaTim Medis Reaksi Cepat, Dr. Cipto Mangunkusumo National General Hospital, IndonesiaIntroduction: Hypotension is an acute complication following Emergency Endotracheal Intubation (ETI) in populations who called the Rapid Response Team (RRT). Thus, a fast and simple tool is needed to identify the risk of Post-emergency Intubation Hypotension (PIH). Shock Index (SI) pre-intubation is one of the potential factors to predict PIH. Objective: To measure the association between shock index with post-emergency intubation hypotension after calling for the RRT. Materials and Methods: This research is a cohort retrospective study that analyzed 171 patients aged ≥18 years who have called RRT and underwent an emergency ETI. The cut-off point for SI was determined using the ROC curve to predict PIH. The modification effect was evaluated using stratification analysis. Data were analyzed using cox regression to determine the likelihood of SI in the cause of hypotension. Result: A total of 92 patients (53.8%) underwent post-emergency intubation hypotension. The SI cut-off point of 0.9 had a sensitivity of 82.6% and a specificity of 67.1% for predicting PIH (Area Under Curve (AUC) 0.81; 95% CI 0.754–0.882, p <0.05). The increased risk of PIH associated with high SI score was an aRR of 1.9; 95% CI 1.03–3.57, a p-value of 0.040 among those with sepsis, and an aRR of 7.9, 95% CI 2.36–26.38, a p-value of 0.001 among those without sepsis. Conclusion: This study showed that a high SI score was associated with PIH after being controlled with other PIH risk variables. The risk of PIH associated with SI score modestly increased (2-fold increase) in those with sepsis and significantly increased (8-fold increase) in those without sepsis.https://e-journal.unair.ac.id/IJAR/article/view/41003critical illnessemergency intubationpost-intubation hypotensionrapid response teamshock index
spellingShingle Herlina Rahmah
Asri Adisasmita
Sidharta Kusuma Manggala
Adhrie Sugiarto
Fadiah Zahrina
Prita Rosdiana
Association Between Shock Index and Post-Emergency Intubation Hypotension in Patients Who Called the Rapid Response Team at Dr. Cipto Mangunkusumo Hospital
Indonesian Journal of Anesthesiology and Reanimation (IJAR)
critical illness
emergency intubation
post-intubation hypotension
rapid response team
shock index
title Association Between Shock Index and Post-Emergency Intubation Hypotension in Patients Who Called the Rapid Response Team at Dr. Cipto Mangunkusumo Hospital
title_full Association Between Shock Index and Post-Emergency Intubation Hypotension in Patients Who Called the Rapid Response Team at Dr. Cipto Mangunkusumo Hospital
title_fullStr Association Between Shock Index and Post-Emergency Intubation Hypotension in Patients Who Called the Rapid Response Team at Dr. Cipto Mangunkusumo Hospital
title_full_unstemmed Association Between Shock Index and Post-Emergency Intubation Hypotension in Patients Who Called the Rapid Response Team at Dr. Cipto Mangunkusumo Hospital
title_short Association Between Shock Index and Post-Emergency Intubation Hypotension in Patients Who Called the Rapid Response Team at Dr. Cipto Mangunkusumo Hospital
title_sort association between shock index and post emergency intubation hypotension in patients who called the rapid response team at dr cipto mangunkusumo hospital
topic critical illness
emergency intubation
post-intubation hypotension
rapid response team
shock index
url https://e-journal.unair.ac.id/IJAR/article/view/41003
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